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Invitrogen
GPNMB Polyclonal Antibody
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FIGURE: 1 / 3
GPNMB Antibody (PA5-115316) in ICC/IF
Product Details
PA5-115316
Species Reactivity
Host/Isotype
Class
Type
Immunogen
Conjugate
Form
Concentration
Purification
Storage buffer
Contains
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RRID
Product Specific Information
Antibody detects endogenous levels of total GPNMB.
Target Information
The protein encoded by this gene is a type I transmembrane glycoprotein which shows homology to the pMEL17 precursor, a melanocyte-specific protein. GPNMB shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines. GPNMB may be involved in growth delay and reduction of metastatic potential. Two transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Bioinformatics
Protein Aliases: DC-HIL; dendritic cell-associated heparin sulfate proteoglycan-dependent integrin ligand; Dendritic cell-associated transmembrane protein; glycoprotein (transmembrane) nmb; glycoprotein nmb-like protein; glycoprotein nonmetastatic melanoma protein B; hematopoietic growth factor inducible neurokinin-1; Hematopoietic growth factor inducible neurokinin-1 type; iris pigment dispersion; Osteoactivin; transmembrane glycoprotein HGFIN; Transmembrane glycoprotein NMB
Gene Aliases: DC-HIL; Dchil; GPNMB; HGFIN; ipd; NMB; UNQ1725/PRO9925
UniProt ID: (Human) Q14956, (Mouse) Q99P91
Entrez Gene ID: (Human) 10457, (Mouse) 93695
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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