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  • GBF1 Antibodies

Invitrogen

GBF1 Polyclonal Antibody

View all (12) GBF1 antibodies

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Datasheet
Protocols
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Datasheet
Protocols
Questions & Answers

Cite GBF1 Polyclonal Antibody

  • Antibody Testing Data (2)
GBF1 Antibody in Immunocytochemistry (ICC/IF)
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GBF1 Antibody in Immunocytochemistry (ICC/IF)
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GBF1 Antibody (PA5-58091) in ICC/IF

Immunofluorecent analysis of GBF1 in human cell line A-431 using GBF1 Polyclonal Antibody (Product # PA5-58091). Staining shows localization to the Golgi apparatus. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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GBF1 Antibody in Immunocytochemistry (ICC/IF)
GBF1 Antibody in Immunohistochemistry (IHC)
GBF1 Polyclonal Antibody

Product Details

PA5-58091

Applications
Tested Dilution
Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:50
-

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL
-
Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human GBF1. Recombinant protein control fragment (Product #RP-97052).
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.2 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2641893

Product Specific Information

Immunogen sequence: INQYSLTVGL DLGPHDTKSL LKCVESLSFI VRDAAHITPD NFELCVKTLR IFVEASLNGG CKSQEKRGKS HKYDSKGNRF K

Highest antigen sequence identity to the following orthologs: Mouse - 96%, Rat - 98%.

Target Information

This gene encodes a member of the Sec7 domain family. The encoded protein is a guanine nucleotide exchange factor that regulates the recruitment of proteins to membranes by mediating GDP to GTP exchange. The encoded protein is localized to the Golgi apparatus and plays a role in vesicular trafficking by activating ADP ribosylation factor 1. The encoded protein has also been identified as an important host factor for viral replication. Multiple transcript variants have been observed for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: BFA-resistant GEF 1; Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1

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Gene Aliases: ARF1GEF; GBF1; KIAA0248

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UniProt ID: (Human) Q92538

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Entrez Gene ID: (Human) 8729

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Function(s)
guanyl-nucleotide exchange factor activity ARF guanyl-nucleotide exchange factor activity protein binding phosphatidylinositol-3,4,5-trisphosphate binding phosphatidylinositol-3,5-bisphosphate binding
Process(es)
cell activation involved in immune response ER to Golgi vesicle-mediated transport retrograde vesicle-mediated transport, Golgi to ER post-Golgi vesicle-mediated transport Golgi to endosome transport Golgi organization regulation of mitotic cell cycle protein transport viral process neutrophil chemotaxis regulation of ARF protein signal transduction protein localization to Golgi apparatus retrograde transport, endosome to Golgi positive regulation of GTPase activity COPI coating of Golgi vesicle establishment of monopolar cell polarity protein localization to endoplasmic reticulum exit site Golgi disassembly endoplasmic reticulum-Golgi intermediate compartment organization reactive oxygen species biosynthetic process protein localization to endoplasmic reticulum tubular network regulation of protein localization to cell surface
It has to be done as per old AB suggested Products section.
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Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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