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Proteintech
GAPDHS Polyclonal Antibody
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Product Details
13937-1-AP
Species Reactivity
Published species
Host/Isotype
Class
Type
Immunogen
Conjugate
Form
Concentration
Purification
Storage buffer
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Product Specific Information
Immunogen sequence: LPPHPATPP PKMVSVAREL TVGINGFGRI GRLVLRACME KGVKVVAVND PFIDPEYMVY MFKYDSTHGR YKGSVEFRNG QLVVDNHEIS VYQCKEPKQI PWRAVGSPYV VESTGVYLSI QAASDHISAG AQRVVISAPS PDAPMFVMGV NENDYNPGSM NIVSNASCTT NCLAPLAKVI HERFGIVEGL MTTVHSYTAT QKTVDGPSRK AWRDGRGAHQ NIIPASTGAA KAVTKVIPEL KGKLTGMAFR VPTPDVSVVD LTCRLAQPAP YSAIKEAVKA AAKGPMAGIL AYTEDEVVST DFLGDTHSSI FDAKAGIALN DNFVKLISWY DNEYGYSHRV VDLLRYMFSR DK (58-408 aa encoded by BC036373)
Target Information
Glyceraldehyde 3-Phosphate Dehydrogenase (GAPDH) is a metabolic enzyme responsible for catalyzing one step in the glycolytic pathway, the reversible oxidative phosphorylation of glyceraldehyde 3-phosphate. Because GAPDH is a protein expressed in large amounts and which is required at all times for important "house keeping" functions, levels of GAPDH mRNA are often measured and used as standards in studies of mRNA expression. Increasingly, scientists are making use of specific antibodies to GAPDH in comparable studies of levels of protein expression. GAPDH is reported to bind to a variety of other proteins, including the amyloid precursor protein, mutations in which cause some forms of Alzheimer's disease, and the polyglutamine tracts of Huntingtin, the protein product aberrant forms of which are causative of Huntington's disease. Associations with actin and tubulin have also been reported. The protein may also have a role in the regulation of apoptosis, and interestingly migrates from the cytoplasm into the nucleus when cells become apoptotic.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: epididymis secretory protein Li 278; GAPDH S; GAPDH-2; glyceraldehyde-3-phosphate dehydrogenase type 2; Glyceraldehyde-3-phosphate dehydrogenase, testis-specific; Spermatogenic cell-specific glyceraldehyde 3-phosphate dehydrogenase 2; Spermatogenic glyceraldehyde-3-phosphate dehydrogenase
Gene Aliases: Gapd-s; GAPD2; GAPDH-2; GAPDH2; GAPDHS; GAPDS; HEL-S-278; HSD-35; HSD35
UniProt ID: (Human) O14556, (Rat) Q9ESV6, (Mouse) Q64467
Entrez Gene ID: (Human) 26330, (Rat) 66020, (Mouse) 14447
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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