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  • GAP43 Antibodies

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GAP 43 Polyclonal Antibody

5 References
View all (45) GAP43 antibodies

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Datasheet
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Datasheet
Protocols
Questions & Answers

Cite GAP 43 Polyclonal Antibody

GAP 43 Polyclonal Antibody

Product Details

OSG00024G-500UG

Applications
Tested Dilution
Publications

Immunohistochemistry (IHC)

10-50 µg/mL
-

Miscellaneous PubMed (MISC)

-
View 5 publications 5 publications
Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

A synthetic peptide from the n-terminal region of human Axonal membrane protein GAP-43 (Neuromodulin, growth-associated protein 43) conjugated to an immunogenic carrier protein was used as the antigen
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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Lyophilized

Concentration

Conc. Not Determined

Purification

Ammonium sulfate precipitation

Storage buffer

PBS

Contains

no preservative

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability.

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Reconstitute in 500 µL of sterile water. Centrifuge to remove any insoluble material.

The peptide is homologous in rat, mouse, zebra fish and chicken.

Specificity of this antibody: GAP-43.

Target Information

GAP43 (Neuromodulin) is associated with nerve growth. GAP43 is expressed by developing and regenerating neurons, and to a lesser extent reactive glial cells. It is a major component of the motile "growth cones" that form the tips of elongating axons. GAP43 also plays a role in axonal and dendritic filopodia induction.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Bioinformatics

Protein Aliases: Axonal membrane protein GAP-43; brain abundant, membrane attached signal protein 2; Calmodulin-binding protein P-57; growth accentuating protein 43; Growth-associated protein 43; MGC156666; nerve growth-related peptide GAP43; Neural phosphoprotein B-50; Neuromodulin; neuron growth-associated protein 43; neuron protein F1; pp46; Protein F1

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Gene Aliases: B-50; Basp2; GAP-43; GAP43; PP46

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UniProt ID: (Human) P17677, (Rat) P07936, (Mouse) P06837

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Entrez Gene ID: (Human) 2596, (Rat) 29423, (Mouse) 14432

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Function(s)
phosphatidylserine binding protein binding calmodulin binding lysophosphatidic acid binding phosphatidylinositol phosphate binding
Process(es)
nervous system development axon guidance glial cell differentiation axon choice point recognition regulation of growth tissue regeneration cell fate commitment regulation of filopodium assembly axon development multicellular organism development cell differentiation protein kinase C-activating G-protein coupled receptor signaling pathway response to wounding
It has to be done as per old AB suggested Products section.
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