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  • Primary Antibodies ›
  • Folate Receptor alpha Antibodies

Invitrogen

Folate Receptor alpha Recombinant Rabbit Monoclonal Antibody (3J6W3)

View all (30) Folate Receptor alpha antibodies

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Datasheet
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Datasheet
Protocols
Questions & Answers

Cite Folate Receptor alpha Recombinant Rabbit Monoclonal Antibody (3J6W3)

Folate Receptor alpha Recombinant Rabbit Monoclonal Antibody (3J6W3)
  • Antibody Testing Data (2)
Folate Receptor alpha Antibody in Western Blot (WB)
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Folate Receptor alpha Antibody in Western Blot (WB)
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Folate Receptor alpha Antibody (MA5-51273) in WB

Western blot analysis of Folate Receptor alpha in extracts of various cell lines. Samples were incubated with Folate Receptor alpha Recombinant monoclonal antibody (Product # MA5-51273) using a dilution of 1:1,000 followed by HRP Goat Anti-Rabbit IgG (H+L) secondary antibody at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Ex... View More {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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Folate Receptor alpha Antibody in Western Blot (WB)
Folate Receptor alpha Antibody in Western Blot (WB)

Product Details

MA5-51273

Applications
Tested Dilution
Publications

Western Blot (WB)

1:1,000-1:2,000
-

ELISA (ELISA)

1 µg/mL
-
Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Expression System

HEK293 cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

3J6W3

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Folate Binding Protein(FBP) / FOLR1 (NP_000793.1).
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.91 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.3, with 0.05% BSA, 50% glycerol

Contains

0.05% ProClin 300

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_3093916

Product Specific Information

Immunogen sequence: MAQRMTTQLL LLLVWVAVVG EAQTRIAWAR TELLNVCMNA KHHKEKPGPE DKLHEQCRPW RKNACCSTNT SQEAHKDVSY LYRFNWNHCG EMAPACKRHF

Target Information

The protein encoded by this gene is a member of the folate receptor family. Members of this gene family bind folic acid and its reduced derivatives, and transport 5-methyltetrahydrofolate into cells. This gene product is a secreted protein that either anchors to membranes via a glycosyl-phosphatidylinositol linkage or exists in a soluble form. Mutations in this gene have been associated with neurodegeneration due to cerebral folate transport deficiency. Due to the presence of two promoters, multiple transcription start sites, and alternative splicing, multiple transcript variants encoding the same protein have been found for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: Adult folate-binding protein; FBP; folate binding protein; folate binding protein 1; Folate receptor 1; folate receptor 1 (adult); Folate receptor alpha; Folate receptor, adult; Folate-binding protein 1; FR-alpha; KB cells FBP; MOv18; Ovarian tumor-associated antigen MOv18

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Gene Aliases: FBP; FBP1; Folbp-1; Folbp1; FOLR; FOLR1

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UniProt ID: (Human) P15328, (Mouse) P35846

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Entrez Gene ID: (Human) 2348, (Rat) 171049, (Mouse) 14275

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Function(s)
receptor activity folic acid binding drug binding folic acid transporter activity methotrexate binding folic acid receptor activity
Process(es)
folic acid transport folic acid metabolic process posttranslational protein targeting to membrane transport heart looping neural crest cell migration involved in heart formation cardiac neural crest cell migration involved in outflow tract morphogenesis ER to Golgi vesicle-mediated transport receptor-mediated endocytosis regulation of transforming growth factor beta receptor signaling pathway axon regeneration COPII vesicle coating regulation of canonical Wnt signaling pathway pharyngeal arch artery morphogenesis anterior neural tube closure cellular response to folic acid
It has to be done as per old AB suggested Products section.
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