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  • FUSIP1 Antibodies

Proteintech

FUSIP1 Polyclonal Antibody

2 References
View all (9) FUSIP1 antibodies

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Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Cite FUSIP1 Polyclonal Antibody

  • Antibody Testing Data (1)
FUSIP1 Antibody in Western Blot (WB)
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FUSIP1 Antibody in Western Blot (WB)
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FUSIP1 Antibody (10131-1-AP) in WB

HepG2 cells were subjected to SDS PAGE followed by western blot with 10131-1-AP (FUSIP1 Antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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FUSIP1 Antibody in Western Blot (WB)

Product Details

10131-1-AP

Applications
Tested Dilution
Publications

Western Blot (WB)

1:1,000
View 2 publications 2 publications
Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

FUSIP1 Fusion Protein Ag0176

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

133 µg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice

Product Specific Information

Aliquoting is unnecessary for -20°C storage.

Target Information

FUSIP1 is a member of the serine-arginine (SR) family of proteins, which is involved in constitutive and regulated RNA splicing. Members of this family are characterized by N-terminal RNP1 and RNP2 motifs, which are required for binding to RNA, and multiple C-terminal SR/RS repeats, which are important in mediating association with other cellular proteins. This protein can influence splice site selection of adenovirus E1A pre-mRNA. It interacts with the oncoprotein TLS, and abrogates the influence of TLS on E1A pre-mRNA splicing.This gene product is a member of the serine-arginine (SR) family of proteins, which is involved in constitutive and regulated RNA splicing. Members of this family are characterized by N-terminal RNP1 and RNP2 motifs, which are required for binding to RNA, and multiple C-terminal SR/RS repeats, which are important in mediating association with other cellular proteins. This protein can influence splice site selection of adenovirus E1A pre-mRNA. It interacts with the oncoprotein TLS, and abrogates the influence of TLS on E1A pre-mRNA splicing. Alternative splicing of this gene results in at least two transcript variants encoding different isoforms. In addition, transcript variants utilizing alternative polyA sites exist.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Bioinformatics

Protein Aliases: 40 kDa SR-repressor protein; FUS interacting protein (serine-arginine rich) 1; FUS interacting protein (serine/arginine-rich) 1; Fus-associated protein with serine-arginine repeats; FUS-interacting protein (serine-arginine rich) 2; FUS-interacting serine-arginine-rich protein 1; Neural-salient serine/arginine-rich protein; neural-salient SR protein; Neural-specific SR protein; protein phosphatase 1, regulatory subunit 149; serine-arginine repressor protein (40 kDa); Serine/arginine-rich splicing factor 10; serine/arginine-rich splicing factor 13A; Splicing factor SRp38; splicing factor, arginine/serine-rich 13; Splicing factor, arginine/serine-rich 13A; SR splicing factor 10; SRrp40; TASR; TLS-associated protein TASR; TLS-associated protein with Ser-Arg repeats; TLS-associated protein with SR repeats; TLS-associated serine-arginine protein; TLS-associated serine-arginine protein 1; TLS-associated serine-arginine protein 2; TLS-associated SR protein

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Gene Aliases: FUSIP1; FUSIP2; NSSR; NSSR1; NSSR2; PPP1R149; SFRS13; SFRS13A; SRp38; SRrp40; SRSF10; Srsf13a; TASR; TASR1; TASR2

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UniProt ID: (Human) O75494, (Mouse) Q9R0U0

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Entrez Gene ID: (Human) 10772, (Rat) 362630, (Mouse) 14105

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Function(s)
nucleotide binding RNA binding protein binding poly(A) RNA binding RS domain binding unfolded protein binding nucleic acid binding
Process(es)
RNA splicing, via transesterification reactions mRNA splicing, via spliceosome mRNA splice site selection cytosolic transport negative regulation of mRNA splicing, via spliceosome spliceosomal tri-snRNP complex assembly regulation of transcription, DNA-templated mRNA export from nucleus regulation of mRNA splicing, via spliceosome mRNA processing RNA splicing
It has to be done as per old AB suggested Products section.
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