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Invitrogen
FTO Recombinant Rabbit Monoclonal Antibody (4A5T6)
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FIGURE: 1 / 8
FTO Antibody (MA5-51209) in IHC (P)
Product Details
MA5-51209
Species Reactivity
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Conjugate
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Product Specific Information
Immunogen sequence: STGTLDYILQ RCQLALQNVC DDVDNDDVSL KSFEPAVLKQ GEEIHNEVEF EWLRQFWFQG NRYRKCTDWW CQPMAQLEAL WKKMEGVTNA VLHEVKREGL PVEQRNEILT AILASLTARQ NLRREWHARC QSRIARTLPA DQKPECRPYW EKDDASMPLP FDLTDIVSEL RGQLLEAK
Target Information
FTO is a novel protein and a member of the non-heme dioxygenase (Fe(II)-and 2-oxoglutarate-dependent dioxygenases) superfamily. Amino acid conservation patterns support this hypothesis and indicates that both 2-oxoglutarate and iron should be important for FTO function. Though not much is yet known about FTO, it is thought that the protein may somehow modify the activity of genes involved in metabolism and fat storage, which in turn may influence a person's risk of obesity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Bioinformatics
Protein Aliases: AlkB homolog 9; Alpha-ketoglutarate-dependent dioxygenase FTO; Fat mass and obesity-associated protein; fatso; m6A(m)-demethylase FTO; MGC5149; mRNA (2'-O-methyladenosine-N(6)-)-demethylase FTO; mRNA N(6)-methyladenosine demethylase FTO; Protein fatso; protein fto; tRNA N1-methyl adenine demethylase FTO; U6 small nuclear RNA (2'-O-methyladenosine-N(6)-)-demethylase FTO; U6 small nuclear RNA N(6)-methyladenosine-demethylase FTO
Gene Aliases: ALKBH9; AW743446; BMIQ14; FTO; GDFD; KIAA1752; mKIAA1752; RGD1305121
UniProt ID: (Human) Q9C0B1, (Rat) Q2A121, (Mouse) Q8BGW1
Entrez Gene ID: (Human) 79068, (Rat) 291905, (Mouse) 26383
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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