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  • FOXA2 Antibodies

OriGene

FOXA2 Monoclonal Antibody (OTI3C10), TrueMAB™

View all (33) FOXA2 antibodies

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Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Cite FOXA2 Monoclonal Antibody (OTI3C10), TrueMAB™

  • Antibody Testing Data (8)
FOXA2 Antibody in Immunocytochemistry (ICC/IF)
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FOXA2 Antibody in Immunocytochemistry (ICC/IF)
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FOXA2 Antibody (CF500073) in ICC/IF

Anti-FOXA2 mouse monoclonal antibody (TA500073) Immunofluorescent staining of HeLa cells transiently transfected by pCMV6-ENTRY FOXA2(RC211408) {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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FOXA2 Antibody in Immunocytochemistry (ICC/IF)
FOXA2 Antibody in Immunocytochemistry (ICC/IF)
FOXA2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
FOXA2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
FOXA2 Antibody in Western Blot (WB)
FOXA2 Antibody in Western Blot (WB)
FOXA2 Antibody in Western Blot (WB)
FOXA2 Antibody in Flow Cytometry (Flow)
FOXA2 Monoclonal Antibody (OTI3C10), TrueMAB™

Product Details

CF500073

Applications
Tested Dilution
Publications

Western Blot (WB)

1:1,000
-

Immunohistochemistry (Paraffin) (IHC (P))

1:50
-

Immunocytochemistry (ICC/IF)

1:50
-

Flow Cytometry (Flow)

1:1,000
-
Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

OTI3C10

Immunogen

Recombinant protein expressed in E.coli corresponding to amino acids 300-458 of human FOXA2
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Lyophilized

Concentration

1 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.3, with 8% trehalose

Contains

no preservative

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

For reconstitution, we recommend adding 100 µL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiments, we strongly recommend performing another round of desalting. (Zeba Spin Desalting Columns, 7KMWCO, 0.5 mL, Product # 89882)

Target Information

FOXA2 is a member of the forkhead class of DNA-binding proteins. These hepatocyte nuclear factors are transcriptional activators for liver-specific genes such as albumin and transthyretin. They also interact with chromatin. Similar family members in mice have roles in the regulation of metabolism and in the differentiation of the pancreas and liver. FOXA2 has been linked to sporadic cases of maturity-onset diabetes of the young. Transcript variants encoding different isoforms have been identified.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: FKHL20; Forkhead box protein A2; hepatic nuclear factor-3-beta; hepatocyte nuclear factor 3, beta; Hepatocyte nuclear factor 3-beta; HNF-3-beta; HNF-3B; MGC19807; RONU; TCF-3B; Transcription factor 3B; WHN

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Gene Aliases: FOXA2; HNF3B; TCF3B

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UniProt ID: (Human) Q9Y261

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Entrez Gene ID: (Human) 3170

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Function(s)
RNA polymerase II core promoter proximal region sequence-specific DNA binding RNA polymerase II transcription factor activity, sequence-specific DNA binding DNA binding transcription factor activity, sequence-specific DNA binding transcription factor binding protein domain specific binding transcription regulatory region DNA binding
Process(es)
positive regulation of transcription from RNA polymerase II promoter by glucose negative regulation of transcription from RNA polymerase II promoter by glucose cell fate specification transcription, DNA-templated regulation of transcription from RNA polymerase II promoter adult locomotory behavior negative regulation of epithelial to mesenchymal transition covalent chromatin modification regulation of blood coagulation endocrine pancreas development negative regulation of glucokinase activity positive regulation of embryonic development negative regulation of sequence-specific DNA binding transcription factor activity positive regulation of transcription, DNA-templated positive regulation of transcription from RNA polymerase II promoter regulation of insulin secretion involved in cellular response to glucose stimulus response to interleukin-6 dopaminergic neuron differentiation primitive streak formation positive regulation of cell-cell adhesion mediated by cadherin positive regulation of gastrulation negative regulation of detection of glucose
It has to be done as per old AB suggested Products section.
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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