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  • Primary Antibodies ›
  • FANCI Antibodies

Invitrogen

FANCI Polyclonal Antibody

Advanced Verification
1 Published Figure
2 References
View all (15) FANCI antibodies

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Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Cite FANCI Polyclonal Antibody

  • Antibody Testing Data (8)
  • Published Figures (1)
  • Advanced Verification (1)
FANCI Antibody in Immunocytochemistry (ICC/IF)
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FANCI Antibody in Immunocytochemistry (ICC/IF)
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FIGURE: 1 / 10

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FANCI Antibody (PA5-59014) in ICC/IF

Immunofluorescence analysis of KIAA1794 was performed using Jurkat cells. The cells were fixed with 4% paraformaldehyde for 10 minutes, permeabilized with 0.1% Triton™ X-100 for 15 minutes, and blocked with 2% BSA for 1 hour at room temperature. The cells were labeled with KIAA1794 Polyclonal Antibody (Product # PA5-59014) at 1:100 dilution in 0.1% BSA, incubated at 4 degree Celsius overnight and then labeled with Goat anti-Rabbit IgG (Heavy Chain) Superclonal™ Secondary Antibody, Alexa Fluor® 488 conjugate (Product # A27034) at a dilution... View More {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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FANCI Antibody in Immunocytochemistry (ICC/IF)
FANCI Antibody in Immunohistochemistry (Paraffin) (IHC (P))
FANCI Antibody in Immunohistochemistry (Paraffin) (IHC (P))
FANCI Antibody in Immunohistochemistry (Paraffin) (IHC (P))
FANCI Antibody in Immunohistochemistry (Paraffin) (IHC (P))
FANCI Antibody in Western Blot (WB)
FANCI Antibody in Western Blot (WB)
FANCI Antibody in ChIP Assay (ChIP)
FANCI Antibody in Western Blot (WB)
FANCI Antibody
FANCI Polyclonal Antibody

Product Details

PA5-59014

Applications
Tested Dilution
Publications

Western Blot (WB)

1 µg/mL
View 1 publication 1 publication

Immunohistochemistry (Paraffin) (IHC (P))

1:200-1:500
-

Immunocytochemistry (ICC/IF)

1:100
View 1 publication 1 publication

ChIP assay (ChIP)

5 µg/mL
-
Product Specifications

Species Reactivity

Human

Published species

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human KIAA1794. Recombinant protein control fragment (Product #RP-98096).
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.6 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2643072

Product Specific Information

Immunogen sequence: YGKGVLSGEE CKKQLINTLC SGRWDQQYVI QLTSMFKDVP LTAEEVEFVV EKALSMFSKM NLQEIPPLVY QLLVLSSKGS RKSVLEGIIA FFSALDKQHN EEQSGDELLD VVTVPSGE

Highest antigen sequence identity to the following orthologs: Mouse - 72%, Rat - 73%.

Target Information

The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group I. Alternative splicing results in two transcript variants encoding different isoforms.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Bioinformatics

Protein Aliases: Fanconi anemia group I protein; Fanconi anemia, complementation group I; Protein FACI

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Gene Aliases: FANCI; KIAA1794

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UniProt ID: (Human) Q9NVI1

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Entrez Gene ID: (Human) 55215

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Function(s)
DNA binding protein binding DNA polymerase binding
Process(es)
mitotic G2 DNA damage checkpoint positive regulation of protein ubiquitination interstrand cross-link repair
It has to be done as per old AB suggested Products section.
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