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Invitrogen
ENPP2 Monoclonal Antibody (A4)
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Product Details
MA5-43839
Species Reactivity
Host/Isotype
Class
Type
Clone
Immunogen
Conjugate
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Purification
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RRID
Target Information
The protein encoded by this gene functions as both a phosphodiesterase, which cleaves phosphodiester bonds at the 5' end of oligonucleotides, and a phospholipase, which catalyzes production of lysophosphatidic acid (LPA) in extracellular fluids. LPA evokes growth factor-like responses including stimulation of cell proliferation and chemotaxis. This gene product stimulates the motility of tumor cells and has angiogenic properties, and its expression is upregulated in several kinds of carcinomas. The gene product is secreted and further processed to make the biologically active form. Several alternatively spliced transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Bioinformatics
Protein Aliases: Autotaxin; autotaxin-t; AutotaxinATX; E-NPP 2; Ectonucleotide pyrophosphatase/phosphodiesterase family member 2; Extracellular lysophospholipase D; FLJ26803; LysoPLD; phosphodiesterase I/nucleotide pyrophosphatase 2; plasma lysophospholipase D
Gene Aliases: ATX; ATX-X; AUTOTAXIN; ENPP2; LysoPLD; NPP2; PD-IALPHA; PDNP2
UniProt ID: (Human) Q13822
Entrez Gene ID: (Human) 5168
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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