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  • ENPP2 Antibodies

Fabgennix

ENPP2 Polyclonal Antibody

View all (21) ENPP2 antibodies

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Datasheet
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Datasheet
Protocols
Questions & Answers

Cite ENPP2 Polyclonal Antibody

  • Antibody Testing Data (1)
ENPP2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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ENPP2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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ENPP2 Antibody (ATX-101AP) in IHC (P)

Rat Small Intestine- ENPP2 Primary Antibody: ATX-101AP; 1:50 dilution in IHC Blocking Buffer. DAB (brown) staining and Hematoxylin QS (blue) counterstain. 40X magnification. FFPE section. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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ENPP2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
ENPP2 Polyclonal Antibody

Product Details

ATX-101AP

Applications
Tested Dilution
Publications

Western Blot (WB)

1:500-1:1,000
-

Immunohistochemistry (Paraffin) (IHC (P))

1:50
-

ELISA (ELISA)

1:10,000
-

Immunoprecipitation (IP)

1:50-1:250
-
Product Specifications

Species Reactivity

Human, Mouse, Non-human primate, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Synthetic peptide taken within amino acid region 778-818 on human Ectonucleotide pyrophosphatase/phosphodiesterase 2 (autotaxin) protein.
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.5-1.5 mg/mL

Purification

Affinity chromatography

Storage buffer

proprietary buffer, pH 7.4-7.8, with 0.5% BSA, 30% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice

Target Information

The protein encoded by this gene functions as both a phosphodiesterase, which cleaves phosphodiester bonds at the 5' end of oligonucleotides, and a phospholipase, which catalyzes production of lysophosphatidic acid (LPA) in extracellular fluids. LPA evokes growth factor-like responses including stimulation of cell proliferation and chemotaxis. This gene product stimulates the motility of tumor cells and has angiogenic properties, and its expression is upregulated in several kinds of carcinomas. The gene product is secreted and further processed to make the biologically active form. Several alternatively spliced transcript variants encoding different isoforms have been identified.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: Autotaxin; autotaxin-t; AutotaxinATX; E-NPP 2; Ectonucleotide pyrophosphatase/phosphodiesterase family member 2; Extracellular lysophospholipase D; FLJ26803; LysoPLD; phosphodiesterase I/nucleotide pyrophosphatase 2; phosphodiesterase I/nucleotide pyrophosphatase 2 (autotaxin); plasma lysophospholipase D

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Gene Aliases: ATX; ATX-X; AUTOTAXIN; ENPP2; LysoPLD; NPP2; Npps2; PD-IALPHA; PDNP2

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UniProt ID: (Human) Q13822, (Mouse) Q9R1E6, (Rat) Q64610

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Entrez Gene ID: (Human) 5168, (Mouse) 18606, (Rat) 84050

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Function(s)
nucleic acid binding phosphodiesterase I activity nucleotide diphosphatase activity lysophospholipase activity scavenger receptor activity calcium ion binding transcription factor binding zinc ion binding hydrolase activity polysaccharide binding alkylglycerophosphoethanolamine phosphodiesterase activity catalytic activity metal ion binding
Process(es)
negative regulation of cell-matrix adhesion lipid metabolic process chemotaxis immune response metabolic process positive regulation of cell proliferation phospholipid catabolic process positive regulation of epithelial cell migration lipid catabolic process regulation of cell migration phosphatidylcholine catabolic process regulation of angiogenesis positive regulation of oligodendrocyte differentiation positive regulation of peptidyl-tyrosine phosphorylation positive regulation of focal adhesion assembly cell chemotaxis nucleic acid phosphodiester bond hydrolysis positive regulation of substrate adhesion-dependent cell spreading positive regulation of lamellipodium morphogenesis receptor-mediated endocytosis estrous cycle cellular response to cadmium ion cellular response to estradiol stimulus response to polycyclic arene phosphate-containing compound metabolic process movement of cell or subcellular component G-protein coupled receptor signaling pathway
It has to be done as per old AB suggested Products section.
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