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Bethyl Laboratories
ELL Polyclonal Antibody
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FIGURE: 1 / 1
ELL Antibody (A301-645A) in IP
Product Details
A301-645A
Species Reactivity
Host/Isotype
Class
Type
Immunogen
Conjugate
Form
Concentration
Purification
Storage buffer
Contains
Storage conditions
Shipping conditions
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Target Information
Elongation factor component of the super elongation complex (SEC), a complex required to increase the catalytic rate of RNA polymerase II transcription by suppressing transient pausing by the polymerase at multiple sites along the DNA. Elongation factor component of the little elongation complex (LEC), a complex required to regulate small nuclear RNA (snRNA) gene transcription by RNA polymerase II and III (PubMed:22195968, PubMed:23932780). Specifically required for stimulating the elongation step of RNA polymerase II- and III-dependent snRNA gene transcription (PubMed:23932780). ELL also plays an early role before its assembly into in the SEC complex by stabilizing RNA polymerase II recruitment/initiation and entry into the pause site. Required to stabilize the pre-initiation complex and early elongation. [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Bioinformatics
Protein Aliases: Eleven-nineteen lysine-rich leukemia protein; ELL gene (11-19 lysine-rich leukemia gene); elongation factor RNA polymerase II; protein phosphatase 1, regulatory subunit 68; RNA polymerase II elongation factor ELL
Gene Aliases: C19orf17; ELL; ELL1; MEN; PPP1R68
UniProt ID: (Human) P55199
Entrez Gene ID: (Human) 8178
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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