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  • EGR1 Antibodies

Invitrogen

EGR1 Monoclonal Antibody (8A6)

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Datasheet
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Datasheet
Protocols
Questions & Answers

Cite EGR1 Monoclonal Antibody (8A6)

  • Antibody Testing Data (1)
EGR1 Antibody in Western Blot (WB)
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EGR1 Antibody in Western Blot (WB)
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EGR1 Antibody (MA5-15620) in WB

Western blot analysis of EGR1 using EGR1 monoclonal antibody (Product # MA5-15620) in EGR1 (AA: 282-433) human IgG Fc transfected HEK293 (1)cell lysate. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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EGR1 Antibody in Western Blot (WB)
EGR1 Monoclonal Antibody (8A6)

Product Details

MA5-15620

Applications
Tested Dilution
Publications

Western Blot (WB)

1:500-1:2,000
-

ELISA (ELISA)

1:10,000
-
Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

8A6

Immunogen

Purified recombinant fragment of human EGR1(aa282-433) expressed in E. Coli.
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

Conc. Not Determined

Storage buffer

ascites

Contains

0.03% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_10984931

Product Specific Information

MA5-15620 targets EGR1 in indirect ELISA, WB applications and shows reactivity with Human samples.

The MA5-15620 immunogen is purified recombinant fragment of human EGR1(aa282-433) expressed in E. Coli.
.

MA5-15620 detects EGR1 which has a predicted molecular weight of approximately 57.5kDa.

Target Information

The protein encoded by this gene belongs to the EGR family of C2H2-type zinc-finger proteins. It is a nuclear protein and functions as a transcriptional regulator. The products of target genes it activates are required for differentitation and mitogenesis. Studies suggest this is a cancer suppresor gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: AT225; Early growth response protein 1; EGR-1; Nerve growth factor-induced protein A; NGFI-A; Transcription factor ETR103; Transcription factor Zif268; Zinc finger protein 225; Zinc finger protein Krox-24

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Gene Aliases: AT225; EGR1; G0S30; KROX-24; KROX24; NGFI-A; TIS8; ZIF-268; ZNF225

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UniProt ID: (Human) P18146

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Entrez Gene ID: (Human) 1958

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Function(s)
transcription regulatory region sequence-specific DNA binding RNA polymerase II regulatory region sequence-specific DNA binding transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding DNA binding transcription factor activity, sequence-specific DNA binding protein binding histone acetyltransferase binding sequence-specific DNA binding metal ion binding
Process(es)
negative regulation of transcription from RNA polymerase II promoter transcription from RNA polymerase II promoter response to glucose T cell differentiation BMP signaling pathway response to insulin regulation of protein sumoylation skeletal muscle cell differentiation regulation of apoptotic process positive regulation of transcription, DNA-templated positive regulation of transcription from RNA polymerase II promoter type I interferon signaling pathway regulation of transcription from RNA polymerase II promoter in response to hypoxia interleukin-1-mediated signaling pathway cellular response to gamma radiation cellular response to heparin cellular response to mycophenolic acid glomerular mesangial cell proliferation positive regulation of glomerular metanephric mesangial cell proliferation negative regulation of canonical Wnt signaling pathway
It has to be done as per old AB suggested Products section.
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Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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