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  • MAPRE3 Antibodies

Proteintech

EB3 Polyclonal Antibody

2 References
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Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Cite EB3 Polyclonal Antibody

  • Antibody Testing Data (8)
EB3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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EB3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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EB3 Antibody (23974-1-AP) in IHC (P)

Immunohistochemistry of paraffin-embedded human skeletal muscle tissue slide using 23974-1-AP ( EB3 antibody at dilution of 1:50 (under 40x lens). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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EB3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
EB3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
EB3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
EB3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
EB3 Antibody in Western Blot (WB)
EB3 Antibody in Western Blot (WB)
EB3 Antibody in Western Blot (WB)
EB3 Antibody in Western Blot (WB)
EB3 Polyclonal Antibody

Product Details

23974-1-AP

Applications
Tested Dilution
Publications

Western Blot (WB)

1:500-1:2,000
View 1 publication 1 publication

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:200
-

Not applicable (N/A)

-
View 1 publication 1 publication
Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

EB3 Fusion Protein Ag21148 (1-281 aa encoded by BC011557)
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.37 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: MAVNVYSTS VTSENLSRHD MLAWVNDSLH LNYTKIEQLC SGAAYCQFMD MLFPGCVHLR KVKFQAKLEH EYIHNFKVLQ AAFKKMGVDK IIPVEKLVKG KFQDNFEFIQ WFKKFFDANY DGKDYNPLLA RQGQDVAPPP NPGDQIFNKS KKLIGTAVPQ RTSPTGPKNM QTSGRLSNVA PPCILRKNPP SARNGGHETD AQILELNQQL VDLKLTVDGL EKERDFYFSK LRDIELICQE HESENSPVIS GIIGILYATE EGFAPPEDDE IEEHQQEDQD EY (1-281 aa encoded by BC011557)

Target Information

EB3 is a 282 amino acid homologue of EB1, a protein known to bind APC (adenomatous polyposis coli). It has been shown to bind to tubulin in vitro and microtubules in vivo. Northern blotting shows expressions to be mainly in brain, and to a lesser degree in muscle. EB3 interacts with APCL, a homologue of the tumor suppressor APC, and this interaction may be involved in the stabilization or extension of microtubules.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Bioinformatics

Protein Aliases: APC binding protein; EB1 protein family member 3; EB3; EBF3; End-binding protein 3; Microtubule-associated protein RP/EB family member 3; microtubule-associated protein, RP/EB family, member 3; RP3

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Gene Aliases: AI790651; EB2; EB3; EBF3; EBF3-S; MAPRE3; RP3

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UniProt ID: (Human) Q9UPY8, (Mouse) Q6PER3, (Rat) Q5XIT1

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Entrez Gene ID: (Human) 22924, (Mouse) 100732, (Rat) 298848

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Function(s)
protein binding microtubule binding identical protein binding
Process(es)
cell cycle mitotic nuclear division positive regulation of cyclin-dependent protein serine/threonine kinase activity positive regulation of transcription, DNA-templated cell division positive regulation of microtubule plus-end binding
It has to be done as per old AB suggested Products section.
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