Disclaimer

Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

  • Primary Antibodies ›
  • EAP2 Antibodies

Invitrogen

EAP2 Polyclonal Antibody

View all (15) EAP2 antibodies

{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}

{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}

{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}

Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Cite EAP2 Polyclonal Antibody

  • Antibody Testing Data (1)
EAP2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
Group 53 Created with Sketch.
EAP2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
Group 53 Created with Sketch.

FIGURE: 1 / 1

{{ $ctrl.currentElement.advancedVerification.fullName }}
{{ $ctrl.currentElement.advancedVerification.text }}

EAP2 Antibody (PA5-50657) in IHC (P)

Immunohistochemical analysis of EAP2 in paraffin embedded Human colon cancer tissue using EAP2 Polyclonal Antibody (Product # PA5-50657) at a 1:40 dilution. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
Published figure supplied by benchsci-logo
PMID: {{$ctrl.currentElement.benchSciPubmedId}}
View Product

{{$ctrl.videoDesc}}

{{$ctrl.videoLongDesc}}

EAP2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

Product Details

PA5-50657

Applications
Tested Dilution
Publications

Western Blot (WB)

1:200-1:1,000
-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200
-
Product Specifications

Species Reactivity

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Synthetic peptide corresponding to a region derived from internal residues of human tyrosyl-DNA phosphodiesterase 2

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

2.6 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.4, with 40% glycerol

Contains

0.05% sodium azide

Storage conditions

-20°C

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2636109

Product Specific Information

The antibody detects endogenous levels of total TDP2 protein.

Target Information

This gene encodes a member of a superfamily of divalent cation-dependent phosphodiesterases. The encoded protein associates with CD40, tumor necrosis factor (TNF) receptor-75 and TNF receptor associated factors (TRAFs), and inhibits nuclear factor-kappa-B activation. This protein has sequence and structural similarities with APE1 endonuclease, which is involved in both DNA repair and the activation of transcription factors.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

References (0)

Have you cited this product in a publication?
Let us know so we can reference it here.
Cite this product

Bioinformatics

Protein Aliases: 5'-Tyr-DNA phosphodiesterase; 5'-tyrosyl-DNA phosphodiesterase; EAPII; ETS1-associated protein 2; ETS1-associated protein II; MGC111021; MGC9099; RP1-30M3.3; TRAF and TNF receptor associated protein; TRAF and TNF receptor-associated protein; Tyr-DNA phosphodiesterase 2; Tyrosyl-DNA phosphodiesterase 2; Tyrosyl-RNA phosphodiesterase; VPg unlinkase

View more View less

Gene Aliases: AD-022; AD022; D13Ertd656e; dJ30M3.3; EAP2; EAPII; hTDP2; TDP2; TTRAP

View more View less

UniProt ID: (Human) O95551, (Mouse) Q9JJX7

View more View less

Entrez Gene ID: (Human) 51567, (Mouse) 56196

View more View less

Function(s)
magnesium ion binding single-stranded DNA binding transcription corepressor activity nuclease activity protein binding manganese ion binding tyrosyl-RNA phosphodiesterase activity 5'-tyrosyl-DNA phosphodiesterase activity cyclic-nucleotide phosphodiesterase activity 3',5'-cyclic-AMP phosphodiesterase activity calmodulin-dependent cyclic-nucleotide phosphodiesterase activity cGMP-stimulated cyclic-nucleotide phosphodiesterase activity cGMP-inhibited cyclic-nucleotide phosphodiesterase activity photoreceptor cyclic-nucleotide phosphodiesterase activity endonuclease activity phosphoric diester hydrolase activity hydrolase activity 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate phosphodiesterase activity metal ion binding inositol phosphosphingolipid phospholipase activity inositol phosphorylceramide phospholipase activity mannosyl-inositol phosphorylceramide phospholipase activity mannosyl-diinositol phosphorylceramide phospholipase activity
Process(es)
DNA repair double-strand break repair cellular response to DNA damage stimulus nucleic acid phosphodiester bond hydrolysis cell surface receptor signaling pathway negative regulation of nucleic acid-templated transcription
It has to be done as per old AB suggested Products section.
guarantee_icon

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

Learn more
help_icon

We're here to help

Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.

Contact tech support

Your items have has been added!


Host server : magellan-search-649bfd9c6b-jlsz7:80/100.66.128.142:80.
git-commit: 6001d82975f0049f9efc09ec70b1b2d89229eeb3
git-url: https://github.com/thermofisher/magellan-search
git-branch: release/2.36.2-2025.09.39-1.0