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  • Decorin Antibodies

Invitrogen

Decorin Polyclonal Antibody

1 Published Figure
1 Reference
View all (28) Decorin antibodies

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Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Cite Decorin Polyclonal Antibody

  • Antibody Testing Data (2)
  • Published Figures (1)
Decorin Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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Decorin Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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FIGURE: 1 / 3

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Decorin Antibody (PA5-19151) in IHC (P)

Immunohistochemistry analysis of Decorin in human breast. Samples were incubated with Decorin polyclonal antibody (Product # PA5-19151) using a dilution of 3.75 µg/mL. Formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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Decorin Antibody in Immunohistochemistry (Paraffin) (IHC (P))
Decorin Antibody in Western Blot (WB)
Decorin Antibody in Western Blot (WB)
Decorin Polyclonal Antibody

Product Details

PA5-19151

Applications
Tested Dilution
Publications

Western Blot (WB)

0.5-2 µg/mL
View 1 publication 1 publication

Immunohistochemistry (Paraffin) (IHC (P))

3.75 µg/mL
-
Product Specifications

Species Reactivity

Human

Host/Isotype

Goat / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Synthetic peptide sequence (KISRVDAASLKGLNN) corresponding to the internal amino acids of DCN (aa 232-247).
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.5 mg/mL

Purification

Ammonium sulfate precipitation

Storage buffer

TBS, pH 7.3, with 0.5% BSA

Contains

0.02% sodium azide

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_10983679

Product Specific Information

This antibody is predicted to react with bovine, porcine and Cavia rodent based on sequence homology.

This antibody is tested in Peptide ELISA: antibody detection limit dilution 8,000.

Target Information

Decorin is a member of the small, leucine-rich proteoglycan (SLRP) family along with biglycan. Found in the interterritorial region of cartilage, decorin interacts with collagen and other matrix proteins to regulate the cartilaginous matrix. It has been shown to interact with fibronectin, thrombospondin, C1q, epidermal growth factor receptor (EGFR), and TGF-b. It is believed that decorin also plays a role in the cell cycle of chondrocytes. The decorin neoepitope fragment has a sequence of PKTLQE, and is generated by MMP-3 or ADAMTS-4 cleavage at Glu154-Leu155 of decorin core protein.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Bioinformatics

Protein Aliases: Bone proteoglycan II; Decorin; dermatan sulphate proteoglycans II; Dermatan sulphate proteoglycans II (DSPG2); PG-S2; PG40; proteoglycan core protein; Small leucine rich protein 1B; small leucine-rich protein 1B

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Gene Aliases: CSCD; DCN; DSPG2; PG40; PGII; PGS2; SLRR1B

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UniProt ID: (Human) P07585

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Entrez Gene ID: (Human) 1634

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Function(s)
protein kinase inhibitor activity protein binding collagen binding glycosaminoglycan binding poly(A) RNA binding protein N-terminus binding extracellular matrix binding
Process(es)
kidney development placenta development negative regulation of protein kinase activity skeletal muscle tissue development aging response to mechanical stimulus organ morphogenesis positive regulation of autophagy negative regulation of endothelial cell migration positive regulation of phosphatidylinositol 3-kinase signaling positive regulation of macroautophagy negative regulation of angiogenesis cytokine-mediated signaling pathway peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan extracellular matrix disassembly extracellular matrix organization glycosaminoglycan metabolic process chondroitin sulfate biosynthetic process chondroitin sulfate catabolic process dermatan sulfate biosynthetic process response to lipopolysaccharide wound healing positive regulation of transcription from RNA polymerase II promoter negative regulation of JAK-STAT cascade positive regulation of mitochondrial depolarization positive regulation of mitochondrial fission negative regulation of vascular endothelial growth factor signaling pathway
It has to be done as per old AB suggested Products section.
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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