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  • Primary Antibodies ›
  • DUOX1 Antibodies

Invitrogen

DUOX1 Polyclonal Antibody

View all (7) DUOX1 antibodies

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Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Cite DUOX1 Polyclonal Antibody

  • Antibody Testing Data (3)
DUOX1 Antibody in Immunohistochemistry (IHC)
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DUOX1 Antibody in Immunohistochemistry (IHC)
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DUOX1 Antibody (PA5-54817) in IHC

Immunohistochemical staining of DUOX1 in human cerebral cortex using DUOX1 Polyclonal Antibody (Product # PA5-54817) shows weak cytoplasmic positivity in a subset of neurons. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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DUOX1 Antibody in Immunohistochemistry (IHC)
DUOX1 Antibody in Immunohistochemistry (IHC)
DUOX1 Antibody in Immunohistochemistry (IHC)

Product Details

PA5-54817

Applications
Tested Dilution
Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200
-
Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human DUOX1. Recombinant protein control fragment (Product #RP-91278).

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2640822

Product Specific Information

Immunogen sequence: QHKEELTWED FHFMLRDHNS ELRFTQLCVK GVEVPEVIKD LCRRASYISQ DMICPSPRVS ARCSRSDIET ELTPQRLQCP MDTDPPQEIR RRFGKKVTSF QP

Highest antigen sequence identity to the following orthologs: Mouse - 84%, Rat - 83%.

Target Information

The protein encoded by this gene is a glycoprotein and a member of the NADPH oxidase family. The synthesis of thyroid hormone is catalyzed by a protein complex located at the apical membrane of thyroid follicular cells. This complex contains an iodide transporter, thyroperoxidase, and a peroxide generating system that includes this encoded protein and DUOX2. This protein is known as dual oxidase because it has both a peroxidase homology domain and a gp91phox domain. Two alternatively spliced transcript variants encoding the same protein have been described for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: Dual oxidase 1; flavoprotein NADPH oxidase; Large NOX 1; Long NOX 1; NADPH thyroid oxidase 1; nicotinamide adenine dinucleotide phosphate oxidase; Thyroid oxidase 1

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Gene Aliases: DUOX; DUOX1; LNOX1; NOXEF1; THOX1

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UniProt ID: (Human) Q9NRD9

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Entrez Gene ID: (Human) 53905

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Function(s)
peroxidase activity calcium ion binding NAD(P)H oxidase activity heme binding NADP binding
Process(es)
thyroid hormone generation response to oxidative stress cytokine-mediated signaling pathway cuticle development hormone biosynthetic process superoxide anion generation hydrogen peroxide catabolic process hydrogen peroxide biosynthetic process response to cAMP oxidation-reduction process cellular oxidant detoxification
It has to be done as per old AB suggested Products section.
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Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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