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  • DLD Antibodies

Invitrogen

DLD Polyclonal Antibody

Advanced Verification
View all (42) DLD antibodies

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Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Cite DLD Polyclonal Antibody

  • Antibody Testing Data (4)
  • Advanced Verification (1)
DLD Antibody in Immunocytochemistry (ICC/IF)
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DLD Antibody in Immunocytochemistry (ICC/IF)
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DLD Antibody (PA5-83742) in ICC/IF

Immunofluorecent analysis of DLD in human cell line U-251 MG using DLD Polyclonal Antibody (Product # PA5-83742). Staining shows localization to mitochondria. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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DLD Antibody in Immunocytochemistry (ICC/IF)
DLD Antibody in Immunohistochemistry (Paraffin) (IHC (P))
DLD Antibody in Immunohistochemistry (Paraffin) (IHC (P))
DLD Antibody in Immunohistochemistry (Paraffin) (IHC (P))
DLD Antibody
DLD Polyclonal Antibody

Product Details

PA5-83742

Applications
Tested Dilution
Publications

Western Blot (WB)

0.04-0.4 µg/mL
-

Immunohistochemistry (Paraffin) (IHC (P))

1:1,000-1:2,500
-

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL
-
Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human DLD. Recombinant protein control fragment (Product #RP-100096).
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.4 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2790894

Product Specific Information

Immunogen sequence: DVVAGPMLAH KAEDEGIICV EGMAGGAVHI DYNCVPSVIY THPEVAWVGK SEEQLKEEGI EYKVGKFPFA ANSRAKTNAD TDGMVK

Target Information

This gene encodes the L protein of the mitochondrial glycine cleavage system. The L protein, also named dihydrolipoamide dehydrogenase, is also a component of the pyruvate dehydrogenase complex, the alpha-ketoglutarate dehydrogenase complex, and the branched-chain alpha-keto acide dehydrogenase complex. Mutations in this gene have been identified in patients with E3-deficient maple syrup urine disease and lipoamide dehydrogenase deficiency.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: diaphorase; Dihydrolipoamide dehydrogenase; Dihydrolipoyl dehydrogenase, mitochondrial; E3 component of pyruvate dehydrogenase complex, 2-oxo-glutarate complex, branched chain keto acid dehydrogenase complex; Glycine cleavage system L protein; glycine cleavage system protein L; lipoamide dehydrogenase; lipoamide reductase; lipoyl dehydrogenase; OTTHUMP00000206744; OTTHUMP00000206746; OTTHUMP00000206748; OTTHUMP00000206749; PH; PHE 3

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Gene Aliases: DLD; DLDD; DLDH; E3; GCSL; LAD; PHE3

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UniProt ID: (Human) P09622

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Entrez Gene ID: (Human) 1738

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Function(s)
dihydrolipoyl dehydrogenase activity pyruvate dehydrogenase (NAD+) activity lipoamide binding flavin adenine dinucleotide binding NAD binding
Process(es)
pyruvate metabolic process tricarboxylic acid cycle 2-oxoglutarate metabolic process mitochondrial electron transport, NADH to ubiquinone proteolysis lysine catabolic process gastrulation aging branched-chain amino acid catabolic process lipoate metabolic process regulation of acetyl-CoA biosynthetic process from pyruvate regulation of membrane potential cell redox homeostasis glyoxylate metabolic process sperm capacitation dihydrolipoamide metabolic process mitochondrial acetyl-CoA biosynthetic process from pyruvate
It has to be done as per old AB suggested Products section.
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