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Bethyl Laboratories
Cytoskeletal Actin Recombinant Rabbit Monoclonal Antibody (BLR057F)
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FIGURE: 1 / 3
Cytoskeletal Actin Antibody (A700-057) in ICC/IF
Product Details
A700-057
Species Reactivity
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Target Information
Beta actin is one of six actin isoforms which have been identified. Beta actin is a non-muscle cytoskeletal protein in all human cell types and is involved in cell motility, structure, and integrity. There are six different actin isoforms in human. The beta isoform of actin, along with gamma actin, coexist in most cell types as components of the cyto-skeleton. Beta actins are cytoplasmic proteins ubuquitously expressed in all eukaryotic cells. Polymerization of globular actin (G-actin) leads to a structural filament (F-actin) in the form of two stranded helix. Actins are highly conserved proteins that are involved in cell motility, structure and integrity. Because beta actin is ubiquitously expressed in all eukaryotic cells, it is frequently used as a loading control for assays involving protein detection, such as Western blotting. Antibodies to beta-actin provide a specific and useful tool in studying the intracellular distribution of beta-actin and the static and dynamic aspects of the cytoskeleton.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: actin, beta; Actin, cytoplasmic 1; Actin, cytoplasmic 2; Atcb; beta actin; beta cytoskeletal actin; Beta-actin; beta-actin FE-3; cytoskeletal gamma-actin; cytoskeleton actin; deafness, autosomal dominant 20; deafness, autosomal dominant 26; epididymis luminal protein 176; gamma actin; Gamma-actin; PS1TP5-binding protein 1
Gene Aliases: ACT; ACTB; ACTG; ACTG1; Actl; Actx; AL023024; beta-actin; BRWS1; BRWS2; DFNA20; DFNA26; E430023M04Rik; E51; HEL-176; PS1TP5BP1
UniProt ID: (Human) P60709, (Human) P63261, (Mouse) P60710, (Mouse) P63260
Entrez Gene ID: (Human) 60, (Human) 71, (Mouse) 11461, (Mouse) 11465
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