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Invitrogen
Cytokeratin 17 Monoclonal Antibody (3B12)
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Product Details
MA5-15534
Species Reactivity
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Conjugate
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Product Specific Information
MA5-15534 targets CK17 in indirect ELISA, IHC and WB applications and shows reactivity with Human samples.
The MA5-15534 immunogen is purified recombinant fragment of CK17 expressed in E. Coli.
MA5-15534 detects CK17 which has a predicted molecular weight of approximately 49kDa.
Target Information
Cytokeratins are a subfamily of intermediate filament proteins and are characterized by a remarkable biochemical diversity, represented in human epithelial tissues by at least 20 different polypeptides. They range in molecular weight between approximately40 kDa and approximately68 kDa and isoelectric pH between 4. 9 - 7. 8. The individual human cytokeratins are numbered 1 to 20. The various epithelia in the human body usually express cytokeratins which are not only characteristic of the type of epithelium, but also related to the degree of maturation or differentiation within an epithelium. Cytokeratin subtype expression patterns are used to an increasing extent in the distinction of different types of epithelial malignancies. The cytokeratin antibodies are not only of assistance in the differential diagnosis of tumors using immunohistochemistry on tissue sections, but are also a useful tool in cytopathology and flow cytometric assays.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Bioinformatics
Protein Aliases: 39.1; CK-17; CK17; Cytokeratin-17; hard keratin; K17; keratin 17, type I; Keratin, type I cytoskeletal 17; Keratin-17
Gene Aliases: 39.1; CK-17; K17; KRT17; PC; PC2; PCHC1
UniProt ID: (Human) Q04695
Entrez Gene ID: (Human) 3872
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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