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  • Primary Antibodies ›
  • CYP4A10/11/14/12A/22 Antibodies

Bioss

Cytochrome P450 4A Polyclonal Antibody

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Datasheet
Protocols
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Datasheet
Protocols
Questions & Answers

Cite Cytochrome P450 4A Polyclonal Antibody

  • Antibody Testing Data (1)
Cytochrome P450 4A Antibody in Western Blot (WB)
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Cytochrome P450 4A Antibody in Western Blot (WB)
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Cytochrome P450 4A Antibody (BS-5054R) in WB

293T lysates probed with CYP4A1 Polyclonal Antibody, Unconjugated (bs-5054R) at 1:300 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at 1:10000 for 60 min at 37°C. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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Cytochrome P450 4A Antibody in Western Blot (WB)

Product Details

BS-5054R

Applications
Tested Dilution
Publications

Western Blot (WB)

1:300
-

Immunohistochemistry (Paraffin) (IHC (P))

1:200
-

Immunohistochemistry (Frozen) (IHC (F))

1:100-1:500
-

Immunocytochemistry (ICC/IF)

1:50-1:200
-

ELISA (ELISA)

1:500-1:1,000
-
Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

KLH conjugated synthetic peptide derived from human Cytochrome P450 4A.

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A

Storage buffer

0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA

Contains

0.02% ProClin 300

Storage conditions

-20°C

Shipping conditions

Ambient (domestic); Wet ice (international)

Target Information

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and hydroxylates medium-chain fatty acids such as laurate and myristate.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: 20-HETE synthase; 20-hydroxyeicosatetraenoic acid synthase; alkane-1 monooxygenase; cyp4a10; cyp4a14; CYP4AII; CYPIVA10; CYPIVA11; CYPIVA12; CYPIVA14; CYPIVA2; CYPIVA22; Cytochrome P-450 K-2; Cytochrome P-450HK-omega; Cytochrome P450 4A10; Cytochrome P450 4A11; Cytochrome P450 4A12A; Cytochrome P450 4A14; Cytochrome P450 4A2; Cytochrome P450 4A22; cytochrome P450 4A22K; cytochrome P450 4A3; Cytochrome P450 K-5; cytochrome P450, 4A1; cytochrome P450, 4a10; cytochrome P450, 4a14; cytochrome P450, family 4, subfamily a, polypeptide 10; cytochrome P450, family 4, subfamily A, polypeptide 11; cytochrome P450, family 4, subfamily a, polypeptide 12; cytochrome P450, family 4, subfamily a, polypeptide 14; cytochrome P450, family 4, subfamily A, polypeptide 22; cytochrome P450, IVA1; cytochrome P450, subfamily 4A, polypeptide 11; cytochrome P450, subfamily IVA, polypeptide 11; Cytochrome P450-LA-omega 1; Cytochrome P450-LA-omega 2; Cytochrome P450-LA-omega 3; Cytochrome P450HL-omega; Cytochrome P452; Fatty acid omega-hydroxylase; Lauric acid hydroxylase; Lauric acid omega-hydroxylase; lauric acid omega-hydroxylase 3; Long-chain fatty acid omega-monooxygenase; P-450 IV4AII; P-450 K-2; P450 K-5; P450-LA-omega 2; P450-LA-omega 3; P450HL-omega

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Gene Aliases: AI314743; AI647584; BC025936; CP4Y; Cyp4a; Cyp4a-1; Cyp4a-10; Cyp4a-2; Cyp4a-3; Cyp4a1; Cyp4a10; CYP4A11; Cyp4a12; Cyp4a12a; Cyp4a14; CYP4A2; CYP4A22; Cyp4a3; CYP4AII; CYPIVA10; CYPIVA3; D4Rp1; RP1

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UniProt ID: (Human) Q02928, (Human) Q5TCH4, (Rat) P08516, (Mouse) O88833, (Mouse) Q91WL5, (Mouse) O35728, (Rat) P20816, (Rat) P20817

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Entrez Gene ID: (Human) 1579, (Human) 284541, (Rat) 50549, (Mouse) 13117, (Mouse) 277753, (Mouse) 13119, (Rat) 24306, (Rat) 298423

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Function(s)
monooxygenase activity iron ion binding arachidonic acid epoxygenase activity alkane 1-monooxygenase activity oxygen binding heme binding leukotriene-B4 20-monooxygenase activity oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen arachidonic acid monooxygenase activity arachidonic acid omega-hydroxylase activity oxidoreductase activity metal ion binding aromatase activity fatty acid binding arachidonic acid binding arachidonic acid 11,12-epoxygenase activity
Process(es)
kidney development response to hormone arachidonic acid metabolic process response to drug linoleic acid metabolic process icosanoid biosynthetic process lauric acid metabolic process oxidation-reduction process long-chain fatty acid metabolic process placenta development renal water homeostasis pressure natriuresis leukotriene metabolic process epoxygenase P450 pathway positive regulation of icosanoid secretion leukotriene B4 catabolic process sodium ion homeostasis fatty acid metabolic process omega-hydroxylase P450 pathway
It has to be done as per old AB suggested Products section.
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