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  • Cyclophilin 40 Antibodies

Invitrogen

Cyclophilin 40 Polyclonal Antibody

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View all (18) Cyclophilin 40 antibodies

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Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Cite Cyclophilin 40 Polyclonal Antibody

  • Antibody Testing Data (8)
  • Advanced Verification (1)
Cyclophilin 40 Antibody in Immunocytochemistry (ICC/IF)
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Cyclophilin 40 Antibody in Immunocytochemistry (ICC/IF)
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Cyclophilin 40 Antibody (PA5-27988) in ICC/IF

Immunofluorescence analysis of 40 kDa Cyclophilin-40 (Peptidylprolyl isomerase D) was performed using 70% confluent log phase A549 cells. The cells were fixed with 4% paraformaldehyde for 10 minutes, permeabilized with 0.1% Triton™ X-100 for 10 minutes, and blocked with 2% BSA for overnight at room temperature. The cells were labeled with Cyclophilin 40 Polyclonal Antibody (Product # PA5-27988) at 1:100 dil... View More {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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Cyclophilin 40 Antibody in Immunocytochemistry (ICC/IF)
Cyclophilin 40 Antibody in Immunocytochemistry (ICC/IF)
Cyclophilin 40 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
Cyclophilin 40 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
Cyclophilin 40 Antibody in Western Blot (WB)
Cyclophilin 40 Antibody in Western Blot (WB)
Cyclophilin 40 Antibody in Western Blot (WB)
Cyclophilin 40 Antibody in Western Blot (WB)
Cyclophilin 40 Antibody

Product Details

PA5-27988

Applications
Tested Dilution
Publications

Western Blot (WB)

1:500-1:3,000
-

Immunohistochemistry (Paraffin) (IHC (P))

1:100-1:1,000
-

Immunocytochemistry (ICC/IF)

1:100-1:1,000
-
Product Specifications

Species Reactivity

Hamster, Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein encompassing a sequence within the center region of human Cyclophilin 40. The exact sequence is proprietary.

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.38 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

0.1M tris glycine, pH 7, with 10% glycerol

Contains

0.01% thimerosal

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2545464

Product Specific Information

Recommended positive controls: HepG2, NIH-3T3.

Predicted reactivity: Mouse (95%), Rat (94%), Pig (91%), Rhesus Monkey (97%), Bovine (91%).

Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Target Information

This gene encodes a H1 histone binding protein that is involved in transporting histones into the nucleus of dividing cells. Multiple isoforms are encoded by transcript variants of this gene. The somatic form is expressed in all mitotic cells, is localized to the nucleus, and is coupled to the cell cycle. The testicular form is expressed in embryonic tissues, tumor cells, and the testis. In male germ cells, this protein is localized to the cytoplasm of primary spermatocytes, the nucleus of spermatids, and the periacrosomal region of mature spermatozoa.

⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: 40 kDa peptidyl-prolyl cis-trans isomerase; 40 kDa peptidyl-prolyl cis-trans isomerase D; cyclophilin 40; cyclophilin D; Cyclophilin-40; Cyclophilin-related protein; Cyp 40; Cyp D; CYP-40; CYP-S1; cytoplasmic cyclophilin D; EC 5.2.1.8; MGC33096; Peptidyl-prolyl cis-trans isomerase D; peptidylprolyl isomerase D; PPIase; PPIase D; rotamase; Rotamase D; S-cyclophilin; SCYLP; testicular tissue protein Li 147

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Gene Aliases: 4930564J03Rik; CYP-40; CYP40; CYPD; I79_011990; PPID; Ppidl; Ppif

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UniProt ID: (Human) Q08752, (Mouse) Q9CR16

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Entrez Gene ID: (Human) 5481, (Mouse) 67738, (Chinese hamster) 100752921

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Function(s)
peptidyl-prolyl cis-trans isomerase activity protein binding transcription factor binding cyclosporin A binding estrogen receptor binding Hsp70 protein binding heat shock protein binding Hsp90 protein binding FK506 binding isomerase activity enzyme binding peptide binding
Process(es)
negative regulation of transcription from RNA polymerase II promoter protein peptidyl-prolyl isomerization protein folding protein complex assembly transport apoptotic process protein transport lipid particle organization regulation of apoptotic process positive regulation of apoptotic process positive regulation of viral genome replication positive regulation of protein secretion chaperone-mediated protein folding cellular response to UV-A viral release from host cell
It has to be done as per old AB suggested Products section.
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