Invitrogen

Copeptin Recombinant Superclonal™ Antibody (20HCLC)

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Datasheet
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Datasheet
Protocols
Questions & Answers
Copeptin Recombinant Superclonal™ Antibody (20HCLC)

Product Details

710321

Applications
Tested Dilution
Publications

Western Blot (WB)

1-2 µg/mL
-
Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Expression System

Expi293

Class

Recombinant Superclonal

Type

Antibody

Clone

20HCLC

Immunogen

Peptide corresponding to amino acids 126-164 of human Copeptin
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.5 mg/mL

Purification

Protein A

Storage buffer

PBS

Contains

0.09% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2532688

Product Specific Information

This antibody is predicted to react with mouse, rat, non-human primate and rabbit based on sequence homology.

Recombinant rabbit Superclonal™ antibodies are unique offerings from Thermo Fisher Scientific. They are comprised of a selection of multiple different recombinant monoclonal antibodies, providing the best of both worlds - the sensitivity of polyclonal antibodies with the specificity of monoclonal antibodies - all delivered with the consistency only found in a recombinant antibody. While functionally the same as a polyclonal antibody - recognizing multiple epitope sites on the target and producing higher detection sensitivity for low abundance targets - a recombinant rabbit Superclonal™ antibody has a known mixture of light and heavy chains. The exact population can be produced in every lot, circumventing the biological variability typically associated with polyclonal antibody production. Note: Formerly called “Recombinant polyclonal antibody”, this product is now rebranded as “Recombinant Superclonal™ antibody”. The physical product and the performance remain unchanged.

Target Information

Copeptin is a member of vasopressin/oxytocin family. It is a 39-amino acid peptide produced from cleavage of preprovasopressin during precursor processing, and is released along with the hormone arginine vasopressin. Copeptin acts to ensure the proper structural formation of arginine vasopressin during precursor processing.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: antidiuretic hormone; AVP-NPII; copeptin; neurohypophyseal; prepro-arginine-vasopressin-neurophysin II; prepro-AVP-NP II; Vasopressin-neurophysin 2-copeptin; vasopressin-neurophysin II-copeptin

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Gene Aliases: ADH; ARVP; AVP; AVP-NPII; AVRP; VP

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UniProt ID: (Human) P01185

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Entrez Gene ID: (Human) 551

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Function(s)
protein kinase activity signal transducer activity receptor binding neuropeptide hormone activity neurohypophyseal hormone activity V1A vasopressin receptor binding V1B vasopressin receptor binding cysteine-type endopeptidase inhibitor activity involved in apoptotic process
Process(es)
maternal aggressive behavior positive regulation of systemic arterial blood pressure renal water homeostasis generation of precursor metabolites and energy water transport apoptotic process signal transduction positive regulation of cytosolic calcium ion concentration cell-cell signaling negative regulation of female receptivity grooming behavior locomotory behavior positive regulation of cell proliferation positive regulation of gene expression positive regulation of glutamate secretion positive regulation of cell growth positive regulation of cAMP biosynthetic process positive regulation of prostaglandin biosynthetic process positive regulation of cellular pH reduction positive regulation of peptidyl-serine phosphorylation response to testosterone response to nicotine social behavior regulation of renal sodium excretion vasoconstriction hyperosmotic salinity response maternal behavior negative regulation of apoptotic process penile erection negative regulation of cysteine-type endopeptidase activity involved in apoptotic process sodium-independent organic anion transport response to ethanol positive regulation of vasoconstriction negative regulation of transmission of nerve impulse ERK1 and ERK2 cascade protein kinase C signaling negative regulation of release of cytochrome c from mitochondria
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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