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Complement fragment 3c Polyclonal Antibody

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Datasheet
Protocols
Questions & Answers

Cite Complement fragment 3c Polyclonal Antibody

Complement fragment 3c Polyclonal Antibody
  • Antibody Testing Data (1)
Complement fragment 3c Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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Complement fragment 3c Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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Complement fragment 3c Antibody (BS-6416R) in IHC (P)

Formalin-fixed and paraffin embedded rat lung labeled with Rabbit Anti-Complement fragment 3c Polyclonal Antibody (bs-6416R) at 1:200 followed by conjugation to the secondary antibody and DAB staining. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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Complement fragment 3c Antibody in Immunohistochemistry (Paraffin) (IHC (P))

Product Details

BS-6416R

Applications
Tested Dilution
Publications

Western Blot (WB)

1:300-1:1,000
-

Immunohistochemistry (Paraffin) (IHC (P))

1:200
-

Immunohistochemistry (Frozen) (IHC (F))

1:100-1:500
-

Immunocytochemistry (ICC/IF)

1:100-1:500
-

ELISA (ELISA)

1:500-1:1,000
-
Product Specifications

Species Reactivity

Human, Mouse, Pig, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

KLH conjugated synthetic peptide derived from human Complement C3c alpha' chain fragment 1, amino acids 1051-1200.
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A

Storage buffer

0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA

Contains

0.02% ProClin 300

Storage conditions

-20°C

Shipping conditions

Ambient (domestic); Wet ice (international)

Target Information

Complement component C3 plays a central role in the activation of complement system. Its activation is required for both classical and alternative complement activation pathways. People with C3 deficiency are susceptible to bacterial infection.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: acylation-stimulating protein cleavage product; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1; C3a anaphylatoxin; Complement C3; complement component C3; complement component C3a; complement component C3b; epididymis secretory sperm binding protein Li 62p; HSE-MSF; prepro-C3

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Gene Aliases: AHUS5; AI255234; ARMD9; ASP; C3; C3a; C3b; C3d; CPAMD1; HEL-S-62p; HSE-MSF; Plp

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UniProt ID: (Rat) P01026, (Human) P01024, (Mouse) P01027, (Pig) P01025

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Entrez Gene ID: (Rat) 24232, (Human) 718, (Mouse) 12266, (Pig) 397072

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Function(s)
endopeptidase inhibitor activity protein binding lipid binding C5L2 anaphylatoxin chemotactic receptor binding cofactor binding serine-type endopeptidase activity receptor binding
Process(es)
positive regulation of type IIa hypersensitivity positive regulation of protein phosphorylation positive regulation of activation of membrane attack complex tolerance induction fatty acid metabolic process chemotaxis inflammatory response complement activation complement activation, alternative pathway complement activation, classical pathway blood coagulation positive regulation of vascular endothelial growth factor production positive regulation of glucose transport regulation of triglyceride biosynthetic process positive regulation of lipid storage negative regulation of endopeptidase activity response to magnesium ion response to estradiol response to progesterone response to estrogen positive regulation of G-protein coupled receptor protein signaling pathway positive regulation of angiogenesis positive regulation of developmental growth positive regulation of phagocytosis response to glucocorticoid positive regulation of ERK1 and ERK2 cascade positive regulation of apoptotic cell clearance proteolysis immune response signal transduction G-protein coupled receptor signaling pathway regulation of complement activation regulation of immune response
It has to be done as per old AB suggested Products section.
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