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  • Complement C3 Antibodies

Invitrogen

Complement C3 Recombinant Rabbit Monoclonal Antibody (23GB1285)

Advanced Verification
View all (29) Complement C3 antibodies

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Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Cite Complement C3 Recombinant Rabbit Monoclonal Antibody (23GB1285)

  • Antibody Testing Data (2)
  • Advanced Verification (1)
Complement C3 Antibody in Immunocytochemistry (ICC/IF)
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Complement C3 Antibody in Immunocytochemistry (ICC/IF)
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Complement C3 Antibody (MA5-53290) in ICC/IF

Immunocytochemistry analysis of Complement C3 in HeLa cells. Nuclei were stained blue with DAPI; Complement C3 recombinant monoclonal antibody (Product # MA5-53290) with a dilution of 1:1,000 was stained magenta with Alexa Fluor 647. Images were taken using Leica stellaris 5. Protein abundance based on laser Intensity and smart gain: Medium. Scale bar: 20 μm. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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Complement C3 Antibody in Immunocytochemistry (ICC/IF)
Complement C3 Antibody in Western Blot (WB)
Complement C3 Antibody
Complement C3 Recombinant Rabbit Monoclonal Antibody (23GB1285)

Product Details

MA5-53290

Applications
Tested Dilution
Publications

Western Blot (WB)

1:1,000-1:5,000
-

Immunocytochemistry (ICC/IF)

1:1,000
-
Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Expression System

HEK293F

Class

Recombinant Monoclonal

Type

Antibody

Clone

23GB1285

Immunogen

A synthesized peptide derived from human C3/C3a (850-900AA).
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_3247763

Target Information

C3 is a key component of the complement system since classical and alternative activation pathways merge at the C3 activation step when C3 is split into C3a and C3b. The molecular mass of C3 is 185 kDa and it consists of two chains (110 kDa and 75 kDa) held together by disulfide bonds.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: acylation-stimulating protein cleavage product; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1; C3a anaphylatoxin; Complement C3; complement component C3a; complement component C3b; epididymis secretory sperm binding protein Li 62p; prepro-C3

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Gene Aliases: AHUS5; ARMD9; ASP; C3; C3a; C3b; CPAMD1; HEL-S-62p

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UniProt ID: (Human) P01024

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Entrez Gene ID: (Human) 718

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Function(s)
serine-type endopeptidase activity endopeptidase inhibitor activity receptor binding protein binding lipid binding C5L2 anaphylatoxin chemotactic receptor binding cofactor binding
Process(es)
positive regulation of type IIa hypersensitivity positive regulation of protein phosphorylation positive regulation of activation of membrane attack complex tolerance induction proteolysis fatty acid metabolic process inflammatory response immune response complement activation complement activation, alternative pathway complement activation, classical pathway signal transduction G-protein coupled receptor signaling pathway blood coagulation positive regulation of vascular endothelial growth factor production positive regulation of glucose transport regulation of triglyceride biosynthetic process positive regulation of lipid storage negative regulation of endopeptidase activity regulation of complement activation response to magnesium ion response to estradiol response to progesterone response to estrogen positive regulation of G-protein coupled receptor protein signaling pathway positive regulation of angiogenesis positive regulation of developmental growth regulation of immune response response to glucocorticoid positive regulation of ERK1 and ERK2 cascade positive regulation of apoptotic cell clearance
It has to be done as per old AB suggested Products section.
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