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  • Chromogranin A Antibodies

Proteintech

Chromogranin A Monoclonal Antibody (3H11C11), CoraLite® 555

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Datasheet
Protocols
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Datasheet
Protocols
Questions & Answers

Cite Chromogranin A Monoclonal Antibody (3H11C11), CoraLite® 555

  • Antibody Testing Data (5)
Chromogranin A Antibody in Immunocytochemistry (ICC/IF)
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Chromogranin A Antibody in Immunocytochemistry (ICC/IF)
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Chromogranin A Antibody (CL555-60135) in ICC/IF

Immunofluorescent analysis of (-20°C Ethanol) fixed SH-SY5Y cells using CoraLite®555 Chromogranin A antibody (CL555-60135, Clone: 3H11C11 ) at dilution of 1:200. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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Chromogranin A Antibody in Immunocytochemistry (ICC/IF)
Chromogranin A Antibody in Immunocytochemistry (ICC/IF)
Chromogranin A Antibody in Immunocytochemistry (ICC/IF)
Chromogranin A Antibody in Flow Cytometry (Flow)
Chromogranin A Antibody in Flow Cytometry (Flow)
Chromogranin A Monoclonal Antibody (3H11C11), CoraLite® 555

Product Details

CL555-60135

Applications
Tested Dilution
Publications

Immunocytochemistry (ICC/IF)

1:50-1:500
-

Flow Cytometry (Flow)

0.8 µg/1x10^6 cell suspension
-
Product Specifications

Species Reactivity

Human, Mouse, Pig, Rat

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

3H11C11

Immunogen

Recombinant protein
View immunogen

Conjugate

CoraLite® 555 CoraLite® 555 CoraLite® 555
  • CoraLite 594
  • CoraLite Plus 488
  • CoraLite Plus 647
  • Request custom conjugation

Excitation/Emission Max

555/570 nm

Form

Liquid

Purification

Protein G

Storage buffer

PBS with 50% glycerol, 0.5% BSA

Contains

0.05% ProClin 300

Storage conditions

-20°C, store in dark

Shipping conditions

Wet ice

Product Specific Information

Immunogen sequence: MQESKAEGNN QAPGEEEEEE EEATNTHPPA SLPSQKYPGP QAEGDSEGLS QGLVDREKGL SAEPGWQAKR EEEEEEEEEA EAGEEAVPEE EGPTVVLNPH PSLGYKEIRK GESRSEALAV DGAGKPGAEE AQDPEGKGEQ EHSQQKEEEE EMAVVPQGLF RGGKSGELEQ EEERLSKEWE DSKRWSKMDQ LAKELTAEKR LEGQEEEEDN RDSSMKLSFR ARAYGFRGPG PQLRRGWRPS SREDSLEAGL PLQVRGYPEE KKEEEGSANR RPEDQELESL SAIEAELEKV AHQLQALRRG

Target Information

Chromogranin A (CHGA) is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. It is found in secretory vesicles of neurons and endocine cells. CHGA is a precursor to three biologically active peptides: vasostatin, pancreastatin, and parastatin. These peptides act as autocine or paracrine negative modulators of the neuroendocrine system. CHGA is an excellent marker for carcinoid tumors, pheo-chromocytomas, paragangliomas, and other neuro-endocrine tumors. Coexpression of chromogranin A and neuron specific enolase (NSE) is common in neuroendocrine neoplasms.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: betagranin (N-terminal fragment of chromogranin A); catestatin; CgA; chromofungin; Chromogranin-A; CTNNB; DKFZp686D02253; FLJ25606; FLJ37923; MGC105435; pancreastatin; parathyroid secretory protein 1; Pituitary secretory protein I; SP-I

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Gene Aliases: CGA; CHGA; ChrA

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UniProt ID: (Pig) P04404, (Human) P10645, (Mouse) P26339

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Entrez Gene ID: (Pig) 397540, (Human) 1113, (Rat) 24258, (Mouse) 12652

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Function(s)
protein binding
Process(es)
regulation of the force of heart contraction organelle organization positive regulation of cAMP metabolic process ovulation cycle negative regulation of vasodilation positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway negative regulation of neuron death mast cell chemotaxis regulation of blood pressure killing of cells of other organism mast cell cytokine production negative regulation of catecholamine secretion mast cell degranulation innate immune response mast cell activation defense response to Gram-negative bacterium defense response to Gram-positive bacterium defense response to fungus positive regulation of cardiac muscle contraction adrenergic receptor signaling pathway involved in cardiac muscle relaxation positive regulation of relaxation of cardiac muscle positive regulation of dense core granule biogenesis
It has to be done as per old AB suggested Products section.
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