Proteintech

Catalase Monoclonal Antibody (1F8D7)

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View all (46) Catalase antibodies

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Datasheet
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Datasheet
Protocols
Questions & Answers
Catalase Monoclonal Antibody (1F8D7)

Product Details

66765-1-IG

Applications
Tested Dilution
Publications

Western Blot (WB)

1:2,000-1:10,000
View 13 publications 13 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:500
-

Immunocytochemistry (ICC/IF)

1:50
View 2 publications 2 publications

Not applicable (N/A)

-
View 1 publication 1 publication
Product Specifications

Species Reactivity

Human, Mouse, Pig, Rat

Published species

Human, Rat

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

1F8D7

Immunogen

Catalase Fusion Protein Ag16916 (228-527 aa encoded by BC112219)
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein G

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: EAVYCKFHY KTDQGIKNLS VEDAARLSQE DPDYGIRDLF NAIATGKYPS WTFYIQVMTF NQAETFPFNP FDLTKVWPHK DYPLIPVGKL VLNRNPVNYF AEVEQIAFDP SNMPPGIEAS PDKMLQGRLF AYPDTHRHRL GPNYLHIPVN CPYRARVANY QRDGPMCMQD NQGGAPNYYP NSFGAPEQQP SALEHSIQYS GEVRRFNTAN DDNVTQVRAF YVNVLNEEQR KRLCENIAGH LKDAQIFIQK KAVKNFTEVH PDYGSHIQAL LDKYNAEKPK NAIHTFVQSG SHLAAREKAN L (228-527 aa encoded by BC112219)

Target Information

Catalase is a homotetrameric heme-containing enzyme present within the matrix of all peroxisomes. It carries out a dismutation reaction in which hydrogen peroxide is converted to water and oxygen. Human catalase has the last four amino acids (-KANL) at the extreme C-terminus for peroxisome targeting. The monomer of human catalase is 61.3 kDa in molecular size. Catalase has been implicated as an important factor in inflammation, mutagenesis, prevention of apoptosis, and stimulation of a wide spectrum of tumors. Loss of catalase leads to the human genetic disease, acatalasemia, or Takahara's disease.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Bioinformatics

Protein Aliases: Catalase; catalase 1; CTA1; HGNC:1516; MGC138422; MGC138424

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Gene Aliases: 2210418N07; Cas-1; Cas1; CAT; Cat01; Catl; Cs-1; CS1

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UniProt ID: (Human) P04040, (Pig) O62839, (Rat) P04762, (Mouse) P24270

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Entrez Gene ID: (Human) 847, (Pig) 397568, (Rat) 24248, (Mouse) 12359

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Function(s)
aminoacylase activity catalase activity receptor binding antioxidant activity oxidoreductase activity, acting on peroxide as acceptor enzyme binding heme binding protein homodimerization activity metal ion binding NADP binding peroxidase activity oxidoreductase activity
Process(es)
response to reactive oxygen species osteoblast differentiation ureteric bud development response to hypoxia purine nucleotide catabolic process triglyceride metabolic process aging cholesterol metabolic process aerobic respiration response to light intensity UV protection response to ozone response to lead ion positive regulation of phosphatidylinositol 3-kinase signaling response to activity response to inactivity hemoglobin metabolic process negative regulation of NF-kappaB transcription factor activity response to estradiol response to insulin response to vitamin A response to vitamin E response to L-ascorbic acid response to drug response to hydrogen peroxide hydrogen peroxide catabolic process negative regulation of apoptotic process response to ethanol response to cadmium ion positive regulation of NF-kappaB transcription factor activity protein tetramerization protein homotetramerization positive regulation of cell division response to hyperoxia response to fatty acid cellular response to growth factor stimulus response to phenylpropanoid cellular oxidant detoxification kidney development response to oxidative stress response to radiation response to UV response to toxic substance oxidation-reduction process
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