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AbboMax
Caspase 2 Polyclonal Antibody
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FIGURE: 1 / 1
Caspase 2 Antibody (500-7174) in IHC (P)
Product Details
500-7174
Species Reactivity
Host/Isotype
Class
Type
Immunogen
Conjugate
Form
Concentration
Purification
Storage buffer
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Shipping conditions
Product Specific Information
Positive control: Jurkat Cells
Cellular location: Cytoplasmic.
Target Information
Caspase 2 gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. The proteolytic cleavage of this protein is induced by a variety of apoptotic stimuli. Alternative splicing of this gene results in multiple transcript variants that encode different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Bioinformatics
Protein Aliases: CASP-2; caspase 2 apoptosis-related cysteine peptidase; caspase 2, apoptosis-related cysteine peptidase (neural precursor cell expressed, developmentally down-regulated 2); caspase 2, apoptosis-related cysteine protease; Caspase-2; cysteine protease caspase-2; ICH-1 protease; ICH-1L; ICH-1L/1S; ICH1 protease; NEDD-2; Neural precursor cell expressed developmentally down-regulated protein 2; Protease ICH-1; protein phosphatase 1, regulatory subunit 57
Gene Aliases: CASP-2; CASP2; ICH-1; ICH-1L/1S; ICH1; ICH1L1S; NEDD-2; NEDD2; PPP1R57
UniProt ID: (Human) P42575, (Chicken) Q98943, (Mouse) P29594, (Rat) P55215
Entrez Gene ID: (Human) 835, (Chicken) 395857, (Mouse) 12366, (Rat) 64314
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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