Invitrogen

Cannabinoid Receptor 1 Recombinant Rabbit Monoclonal Antibody (PSH02-43)

Name: Cannabinoid Receptor 1 Recombinant Rabbit Monoclonal Antibody (PSH02-43)
Brand: Invitrogen
SKU: MA5-52083

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View all (21) Cannabinoid Receptor 1 antibodies

Datasheet

Protocols

Questions & Answers

Datasheet

Protocols

Questions & Answers

Antibody Testing Data (10)
Advanced Verification (3)

Cannabinoid Receptor 1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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Cannabinoid Receptor 1 Antibody (MA5-52083) in IHC (P)

Immunohistochemical analysis of Cannabinoid Receptor 1 was performed using formalin-fixed paraffin-embedded mouse brain and liver tissue sections. To expose the target protein, heat-induced epitope retrieval was performed on de-paraffinized sections using eBioscience™ IHC Antigen Retrieval Solution - High pH (10X) (Product # 00-4956-58) diluted to 1X solution in water in a decloaking chamber at 110 degree C... View More

Cannabinoid Receptor 1 Antibody in Western Blot (WB)

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Immunogen image

Immunogen Image Cannabinoid Receptor 1 Recombinant Rabbit Monoclonal Antibody (PSH02-43)

Product Details

MA5-52083

Applications

Tested Dilution

Publications

Western Blot (WB)

1:2,000

Immunohistochemistry (Paraffin) (IHC (P))

1:200-1:1,000

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Expression System

HEK293 cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

PSH02-43

Immunogen

Recombinant protein within human Cannabinoid receptor 1 aa 1-472.

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A

Storage buffer

PBS, pH 7.4, with 0.1% BSA, 40% glycerol

Contains

0.05% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

AB_3099397

Product Specific Information

Tissue Specificity: Human brain tissue lysate, mouse brain tissue lysate, mouse cerebellum tissue lysate, rat brain tissue lysate, rat cerebellum tissue lysate, mouse brain tissue, mouse hippocampus tissue, rat brain tissue, rat hippocampus tissue.

Positive Control: Human brain tissue lysate, mouse brain tissue lysate, mouse cerebellum tissue lysate, rat brain tissue lysate, rat cerebellum tissue lysate, mouse brain tissue, mouse hippocampus tissue, rat brain tissue, rat hippocampus tissue.

Subcellular Location: Cell membrane, Membrane raft, Mitochondrion outer membrane, Cell projection, axon, Presynapse.

Predicted band size: 53 kDa.

Target Information

This gene encodes one of two cannabinoid receptors. The cannabinoids, principally delta-9-tetrahydrocannabinol and synthetic analogs, are psychoactive ingredients of marijuana. The cannabinoid receptors are members of the guanine-nucleotide-binding protein coupled receptor family, which inhibit adenylate cyclase activity in a dose-dependent, stereoselective and pertussis toxin-sensitive manner. The two receptors have been found to be involved in the cannabinoid-induced CNS effects experienced by users of marijuana. Multiple transcript variants encoding two different protein isoforms have been described for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: Brain-type cannabinoid receptor; CANN6; Cannabinoid receptor 1; cannabinoid receptor 1 (brain); CB-R; CB1; CB1 receptor; central cannabinoid receptor; HGNC:2159; OTTHUMP00000016839; RP1-23D17.1; striatal cannabinoid receptor type 1 protein

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Gene Aliases: CANN6; CB-R; CB1; CB1A; CB1K5; CB1R; CNR; CNR1; Skr6; SKR6R

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UniProt ID: (Human) P21554, (Mouse) P47746, (Rat) P20272

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Entrez Gene ID: (Human) 1268, (Mouse) 12801, (Rat) 25248

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Function(s)

cannabinoid receptor activity drug binding signal transducer activity G-protein coupled receptor activity protein binding

Process(es)

positive regulation of acute inflammatory response to antigenic stimulus G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger adenylate cyclase-modulating G-protein coupled receptor signaling pathway spermatogenesis axonal fasciculation aging response to nutrient memory positive regulation of neuron projection development sensory perception of pain positive regulation of fever generation negative regulation of fatty acid beta-oxidation regulation of synaptic transmission, GABAergic response to lipopolysaccharide negative regulation of mast cell activation negative regulation of dopamine secretion response to nicotine cannabinoid signaling pathway response to cocaine glucose homeostasis positive regulation of apoptotic process negative regulation of ion transport response to morphine response to ethanol negative regulation of action potential negative regulation of blood pressure positive regulation of blood pressure regulation of insulin secretion negative regulation of nitric-oxide synthase activity regulation of synaptic transmission, glutamatergic maternal process involved in female pregnancy regulation of feeding behavior regulation of penile erection signal transduction G-protein coupled receptor signaling pathway learning or memory regulation of lipid metabolic process

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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Cannabinoid Receptor 1 Recombinant Rabbit Monoclonal Antibody (PSH02-43)

Cannabinoid Receptor 1 Antibody (MA5-52083) in IHC (P)

Product Details

MA5-52083

Western Blot (WB)

Immunohistochemistry (Paraffin) (IHC (P))

Species Reactivity

Host/Isotype

Expression System

Class

Type

Clone

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

RRID

Product Specific Information

Target Information

References (0)

Bioinformatics

Performance Guarantee

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