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  • Primary Antibodies ›
  • H-cadherin Antibodies

Bethyl Laboratories

Cadherin 13/CDH13/T-cadherin Polyclonal Antibody

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Datasheet
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Datasheet
Protocols
Questions & Answers

Cite Cadherin 13/CDH13/T-cadherin Polyclonal Antibody

  • Antibody Testing Data (1)
Cadherin 13/CDH13/T-cadherin Antibody in Immunoprecipitation (IP)
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Cadherin 13/CDH13/T-cadherin Antibody in Immunoprecipitation (IP)
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Cadherin 13/CDH13/T-cadherin Antibody (A304-967A) in IP

Detection of human Cadherin 13 by western blot of immunoprecipitates. Samples: Whole cell lysate (0.5 or 1.0 mg per IP reaction; 20% of IP loaded) from HeLa cells prepared using NETN lysis buffer. Antibodies: Affinity purified rabbit anti-Cadherin 13 antibody (Product # A304-967A) (lot 1) used for IP at 6 µg per reaction. Cadherin 13 was also immunoprecipitated by rabbit anti-Cadherin 13 antibody BL19625. F... View More {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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Cadherin 13/CDH13/T-cadherin Antibody in Immunoprecipitation (IP)
Cadherin 13/CDH13/T-cadherin Polyclonal Antibody

Product Details

A304-967A

Applications
Tested Dilution
Publications

Western Blot (WB)

Assay-dependent
-

Immunoprecipitation (IP)

2-10 µg/mg lysate
-
Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Region between residue 475 to 525 of human Cadherin-13.
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

tris citrate/phosphate, pH 7-8

Contains

0.09% sodium azide

Storage conditions

4°C

Shipping conditions

Wet ice

Product Specific Information

The recommended shelf life for this product is 1 year from date of receipt.

Target Information

The protein encoded by this gene has a C-terminal domain with tRNA 3 processing endoribonuclease activity, which catalyzes the removal of the 3' trailer from precursor tRNAs. The protein also interacts with activated Smad family member 2 (Smad2) and its nuclear partner forkhead box H1 (also known as FAST-1), and reduced expression can suppress transforming growth factor-beta induced growth arrest. Mutations in this gene result in an increased risk of prostate cancer. Multiple transcript variants encoding different isoforms have been found for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: CAD13; cadherin 13, H-cadherin (heart); Cadherin-13; CD39 antigen-like 3; CD39-like 3; CD39L3; ecto-apyrase 3; ecto-ATPase 3; ecto-ATPDase 3; H-cadherin; H-cadherin (heart); HB6; Heart cadherin; heart-cadherin; NTPDase 3; NTPDase-3; P105; T cad; T Cadherin; T-cad; T-cadherin; Truncated cadherin; truncated-cadherin

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Gene Aliases: CDH13; CDHH; P105

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UniProt ID: (Human) P55290

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Entrez Gene ID: (Human) 1012

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Function(s)
calcium ion binding low-density lipoprotein particle binding protein homodimerization activity cadherin binding adiponectin binding lipoprotein particle binding
Process(es)
mitotic cell cycle positive regulation of endothelial cell proliferation positive regulation of cell-matrix adhesion sprouting angiogenesis homophilic cell adhesion via plasma membrane adhesion molecules negative regulation of cell adhesion Rho protein signal transduction negative regulation of cell proliferation calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules Rac protein signal transduction lamellipodium assembly regulation of endocytosis positive regulation of cell migration adherens junction organization regulation of epidermal growth factor receptor signaling pathway endothelial cell migration keratinocyte proliferation positive regulation of transcription from RNA polymerase II promoter positive regulation of smooth muscle cell proliferation positive regulation of calcium-mediated signaling positive regulation of positive chemotaxis localization within membrane low-density lipoprotein particle mediated signaling
It has to be done as per old AB suggested Products section.
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