Proteintech

Cadherin-13 Polyclonal Antibody

Name: Cadherin-13 Polyclonal Antibody
Brand: Proteintech
SKU: 12618-1-AP

View all (20) H-cadherin antibodies

Datasheet

Protocols

Questions & Answers

Datasheet

Protocols

Questions & Answers

Antibody Testing Data (8)

Cadherin-13 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

FIGURE: 1 / 8

Cadherin-13 Antibody (12618-1-AP) in IHC (P)

Immunohistochemistry of paraffin-embedded human endometrial cancer using 12618-1-AP (Cadherin-13 antibody) at dilution of 1:100 (under 10x lens).

Cadherin-13 Antibody in Western Blot (WB)

Cadherin-13 Antibody in Flow Cytometry (Flow)

Cadherin-13 Antibody in Immunoprecipitation (IP)

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Immunogen image

Immunogen Image Cadherin-13 Polyclonal Antibody

Product Details

12618-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:200

Flow Cytometry (Flow)

0.5 µg/1x10^6 cells

Immunoprecipitation (IP)

0.5-4.0 µg

Product Specifications

Species Reactivity

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Cadherin-13 Fusion Protein Ag3295 (364-713 aa encoded by BC030653)

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.22 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: TKKEFQATV EEGAVGVIVN LTVEDKDDPA TGAWRAAYTI INGNPGQSFE IHTNPQTNEG MLSVVKPLDY EISAFHTLLI KVENEDPLVP DVSYGPSSTA TVHITVLDVN EGPVFYPDPM MVTRQEDLSV GSVLLTVNAT DPDSLQHQTI RYSVYKDPAG WLNINPINGT VDTTAVLDRE STFVDNSVYT ALFLAIDSGN PPATGTGTLL ITLEDVNDNA PFIYPTVAEV CDDAKNLSVV ILGASDKDLH PNTDPFKFEI HKQAVPDKVW KISKINNTHA LVSLLQNLNK ANYNLPIMVT DSGKPPMTNI TDLRVQVCSC RNSKVDCNAA GALRFSLPSV LLLSLFSLAC L (364-713 aa encoded by BC030653)

Target Information

The protein encoded by this gene has a C-terminal domain with tRNA 3 processing endoribonuclease activity, which catalyzes the removal of the 3' trailer from precursor tRNAs. The protein also interacts with activated Smad family member 2 (Smad2) and its nuclear partner forkhead box H1 (also known as FAST-1), and reduced expression can suppress transforming growth factor-beta induced growth arrest. Mutations in this gene result in an increased risk of prostate cancer. Multiple transcript variants encoding different isoforms have been found for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: CAD13; cadherin 13, H-cadherin (heart); Cadherin-13; CD39 antigen-like 3; CD39-like 3; CD39L3; ecto-apyrase 3; ecto-ATPase 3; ecto-ATPDase 3; H-cadherin; H-cadherin (heart); HB6; Heart cadherin; heart-cadherin; NTPDase 3; NTPDase-3; P105; T cad; T Cadherin; T-cad; T-cadherin; Truncated cadherin; truncated-cadherin

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Gene Aliases: 4932416G01Rik; CDH13; CDHH; Cdht; P105; T-cadherin; Tcad

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UniProt ID: (Human) P55290, (Mouse) Q9WTR5

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Entrez Gene ID: (Human) 1012, (Mouse) 12554

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Function(s)

calcium ion binding low-density lipoprotein particle binding protein homodimerization activity cadherin binding adiponectin binding lipoprotein particle binding protein binding metal ion binding

Process(es)

mitotic cell cycle positive regulation of endothelial cell proliferation positive regulation of cell-matrix adhesion sprouting angiogenesis homophilic cell adhesion via plasma membrane adhesion molecules negative regulation of cell adhesion Rho protein signal transduction negative regulation of cell proliferation calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules Rac protein signal transduction lamellipodium assembly regulation of endocytosis positive regulation of cell migration adherens junction organization regulation of epidermal growth factor receptor signaling pathway endothelial cell migration keratinocyte proliferation positive regulation of transcription from RNA polymerase II promoter positive regulation of smooth muscle cell proliferation positive regulation of calcium-mediated signaling positive regulation of positive chemotaxis localization within membrane low-density lipoprotein particle mediated signaling regulation of cell growth cell adhesion

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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Cadherin-13 Polyclonal Antibody

Cadherin-13 Antibody (12618-1-AP) in IHC (P)

Product Details

12618-1-AP

Western Blot (WB)

Immunohistochemistry (Paraffin) (IHC (P))

Flow Cytometry (Flow)

Immunoprecipitation (IP)

Species Reactivity

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

References (0)

Bioinformatics

Performance Guarantee

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