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  • CYSLTR2 Antibodies

Invitrogen

CYSLTR2 Polyclonal Antibody

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Cite CYSLTR2 Polyclonal Antibody

  • Antibody Testing Data (1)
CYSLTR2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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CYSLTR2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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CYSLTR2 Antibody (PA5-32717) in IHC (P)

Immunohistochemistry analysis of CYSLTR2 in human heart. Samples were incubated with CYSLTR2 polyclonal antibody (Product # PA5-32717). Formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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CYSLTR2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

Product Details

PA5-32717

Applications
Tested Dilution
Publications

Immunohistochemistry (Paraffin) (IHC (P))

10 µg/mL
-

ELISA (ELISA)

Assay-dependent
-
Product Specifications

Species Reactivity

Horse, Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Synthetic 17 amino acid peptide from 1st extracellular domain of human CYSLTR2 / CYSLT2.

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS

Contains

0.1% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2550180

Product Specific Information

Percent identity with other species by BLAST analysis: Human, Gibbon, Marmoset, Horse (100%); Gorilla, Monkey, Mouse, Panda (94%); Dog, Bovine, Hamster, Elephant, Rabbit, Opossum (88%); Pig (82%).

For IHC(P), use heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen.

Target Information

Receptor for cysteinyl leukotrienes. The response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. Stimulation by BAY u9773, a partial agonist, induces specific contractions of pulmonary veins and might also have an indirect role in the relaxation of the pulmonary vascular endothelium. The rank order of affinities for the leukotrienes is LTC4 = LTD4 >> LTE4.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: CysLT(2); CysLT-2; CysLTR2; cysteinyl leukotriene CysLT2 receptor; Cysteinyl leukotriene receptor 2; G-protein coupled receptor GPCR21; G-protein coupled receptor HG57; hGPCR21; HPN321

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Gene Aliases: CYSLT2; CYSLT2R; CYSLTR2; GPCR21; HG57; hGPCR21; HPN321; KPG_011; PSEC0146

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UniProt ID: (Human) Q9NS75

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Entrez Gene ID: (Human) 57105

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Function(s)
cysteinyl leukotriene receptor activity leukotriene receptor activity protein binding G-protein coupled peptide receptor activity
Process(es)
immune response phospholipase C-activating G-protein coupled receptor signaling pathway neuropeptide signaling pathway positive regulation of cell death positive regulation of angiogenesis leukotriene signaling pathway positive regulation of ERK1 and ERK2 cascade
It has to be done as per old AB suggested Products section.
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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