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Invitrogen
CYP4X1 Polyclonal Antibody
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CYP4X1 Antibody (PA5-101319) in IHC (P)
Product Details
PA5-101319
Species Reactivity
Host/Isotype
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Type
Immunogen
Conjugate
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Purification
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Product Specific Information
Antibody detects endogenous levels of total Cytochrome P450 4X1.
Target Information
Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1. A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma. The CYP4X1 gene product has been provisionally designated CYP4X1 pending further characterization.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Bioinformatics
Protein Aliases: CP4X1; CYPIVX1; Cytochrome P450 4X1; cytochrome P450, 4x1; cytochrome P450, family 4, subfamily X, polypeptide 1; EC 1.14.14.1; PRO4404; UNQ1929
Gene Aliases: A230025G20; Cyp4a28-ps; CYP4X1; CYP_a; CYPIVX1; UNQ1929/PRO4404
UniProt ID: (Human) Q8N118, (Rat) Q8K4D6, (Mouse) Q6A152
Entrez Gene ID: (Human) 260293, (Rat) 246767, (Mouse) 81906
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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