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Invitrogen
CYP46A1 Polyclonal Antibody
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FIGURE: 1 / 4
CYP46A1 Antibody (PA3-16810) in ICC/IF
Product Details
PA3-16810
Species Reactivity
Host/Isotype
Class
Type
Immunogen
Conjugate
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Concentration
Storage buffer
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RRID
Product Specific Information
This antibody does not react with mouse samples.
Suggested positive control: antigen standard for CYP46A1 (transient overexpression lysate).
Target Information
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein is expressed in the brain, where it converts cholesterol to 24S-hydroxycholesterol. While cholesterol cannot pass the blood-brain barrier, 24S-hydroxycholesterol can be secreted in the brain into the circulation to be returned to the liver for catabolism.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Bioinformatics
Protein Aliases: CH24H; Cholesterol 24-hydroxylase; Cholesterol 24-monooxygenase; Cholesterol 24S-hydroxylase; Cytochrome P450 46A1; cytochrome P450, family 46, subfamily A, polypeptide 1; cytochrome P450, subfamily 46 (cholesterol 24-hydroxylase)
Gene Aliases: CP46; CYP46; CYP46A1
UniProt ID: (Human) Q9Y6A2
Entrez Gene ID: (Human) 10858
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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