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Invitrogen
CYP2A6/CYP2A7/CYP2A13 Polyclonal Antibody
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Product Details
PA5-99833
Species Reactivity
Host/Isotype
Class
Type
Immunogen
Conjugate
Form
Concentration
Purification
Storage buffer
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Shipping conditions
RRID
Product Specific Information
Antibody detects endogenous levels of total Cytochrome P450 2A6/7/13.
Target Information
The cytochrome P450 (P450) superfamily of enzymes is one of three enzyme systems which metabolize the fatty acid arachadonic acid (AA) to regulators of vascular tone. P450 enzymes are monooxygenase enzymes which require several co-factors such as nicotinamide adenine dinucleotide phosphate (NADPH) and P450 reductase. There are over 200 known genes which encode P450s. Epoxygenases are those P450s which metabolize AA to epoxyeicosatrienoic acid (EETs) and omega-hydroxylases are those P450s which produce 19- and 20-hydroxyeicosatetraenoic acids (19- and 20-HETE). As well as fatty acid metabolism, P450s also metabolize many drugs and toxins. Cytochrome P450 3A4 is abundantly expressed in liver and small intestine and is inducible by barbiturates, glucocorticoids and rifampicin.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Bioinformatics
Protein Aliases: 1,4-cineole 2-exo-monooxygenase; Coumarin 7-hydroxylase; CYPIIA13; CYPIIA6; CYPIIA7; Cytochrome P450 2A13; Cytochrome P450 2A6; Cytochrome P450 2A7; Cytochrome P450 IIA3; Cytochrome P450 IIA4; Cytochrome P450(I); cytochrome P450, family 2, subfamily A, polypeptide 13; cytochrome P450, family 2, subfamily A, polypeptide 6; cytochrome P450, family 2, subfamily A, polypeptide 7; cytochrome P450, subfamily IIA (phenobarbital-inducible), polypeptide 13; cytochrome P450, subfamily IIA (phenobarbital-inducible), polypeptide 6; cytochrome P450, subfamily IIA (phenobarbital-inducible), polypeptide 7; cytochrome P450IIA4; flavoprotein-linked monooxygenase; xenobiotic monooxygenase
Gene Aliases: CPA6; CPA7; CPAD; CYP2A; CYP2A13; CYP2A3; CYP2A6; CYP2A7; CYPIIA13; CYPIIA6; CYPIIA7; P450-IIA4; P450C2A; P450PB
UniProt ID: (Human) Q16696, (Human) P11509, (Human) P20853
Entrez Gene ID: (Human) 1553, (Human) 1548, (Human) 1549
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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