Invitrogen

CYP26B1 Polyclonal Antibody

View all (11) CYP26B1 antibodies

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Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Product Details

PA5-28159

Applications
Tested Dilution
Publications

Western Blot (WB)

1:500-1:3,000
-

Immunohistochemistry (IHC)

Assay-dependent
-
Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein encompassing a sequence within the center region of human CYP26B1. The exact sequence is proprietary.

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7, with 20% glycerol

Contains

0.025% ProClin 300

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2545635

Product Specific Information

Recommended positive controls: HepG2.

Predicted reactivity: Mouse (94%), Rat (94%), Bovine (94%).

Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Target Information

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases that catalyze many reactions involved in drug metabolism and the synthesis of cholesterol, steroids and other lipids. The enzyme encoded by this gene is involved in the specific inactivation of all-trans-retinoic acid to hydroxylated forms, such as 4-oxo-, 4-OH-, and 18-OH-all-trans-retinoic acid.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: Cytochrome P450 26A2; Cytochrome P450 26B1; cytochrome P450 family 26 subfamily A member 1; Cytochrome P450 retinoic acid-inactivating 2; cytochrome P450 retinoid metabolizing protein; cytochrome P450, 26, retinoic acid B1; cytochrome P450, family 26, subfamily B, polypeptide 1; cytochrome P450, subfamily XXVIB, polypeptide 1; Cytochrome P450RAI-2; P450 26A2; retinoic acid B1; retinoic acid hydroxylase; Retinoic acid-metabolizing cytochrome

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Gene Aliases: CP26; CYP26A2; CYP26B1; P450RAI-2; P450RAI2; RHFCA

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UniProt ID: (Human) Q9NP41, (Mouse) Q811W2, (Rat) G3V7X8

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Entrez Gene ID: (Human) 56603, (Mouse) 232174, (Rat) 312495

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Function(s)
retinoic acid binding iron ion binding retinoic acid 4-hydroxylase activity oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen heme binding monooxygenase activity oxidoreductase activity oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen fluorene oxygenase activity mono-butyltin dioxygenase activity tri-n-butyltin dioxygenase activity di-n-butyltin dioxygenase activity methylsilanetriol hydroxylase activity methyl tertiary butyl ether 3-monooxygenase activity 4-nitrocatechol 4-monooxygenase activity 4-chlorophenoxyacetate monooxygenase activity tert-butanol 2-monooxygenase activity alpha-pinene monooxygenase activity dimethylsilanediol hydroxylase activity ammonia monooxygenase activity hydroxymethylsilanetriol oxidase activity 2-hydroxyisobutyrate 3-monooxygenase activity alpha-pinene dehydrogenase activity bisphenol A hydroxylase B activity 2,2-bis(4-hydroxyphenyl)-1-propanol hydroxylase activity 9-fluorenone-3,4-dioxygenase activity anthracene 9,10-dioxygenase activity 2-(methylthio)benzothiazole monooxygenase activity 2-hydroxybenzothiazole monooxygenase activity benzothiazole monooxygenase activity 2,6-dihydroxybenzothiazole monooxygenase activity pinacolone 5-monooxygenase activity thioacetamide S-oxygenase activity thioacetamide S-oxide S-oxygenase activity endosulfan monooxygenase I activity N-nitrodimethylamine hydroxylase activity 4-(1-ethyl-1,4-dimethyl-pentyl)phenol monoxygenase activity endosulfan ether monooxygenase activity pyrene 4,5-monooxygenase activity pyrene 1,2-monooxygenase activity 1-hydroxypyrene 6,7-monooxygenase activity 1-hydroxypyrene 7,8-monooxygenase activity phenylboronic acid monooxygenase activity spheroidene monooxygenase activity metal ion binding
Process(es)
cell fate determination establishment of T cell polarity vitamin metabolic process xenobiotic metabolic process inflammatory response male meiosis spermatogenesis proximal/distal pattern formation positive regulation of gene expression embryonic limb morphogenesis retinoic acid catabolic process tongue morphogenesis regulation of T cell differentiation retinoic acid receptor signaling pathway negative regulation of retinoic acid receptor signaling pathway oxidation-reduction process bone morphogenesis establishment of skin barrier cornification cellular response to retinoic acid positive regulation of tongue muscle cell differentiation retinoic acid metabolic process regulation of retinoic acid receptor signaling pathway
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