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Invitrogen
CYP11B2 Polyclonal Antibody
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Product Details
PA5-67694
Species Reactivity
Host/Isotype
Class
Type
Immunogen
Conjugate
Form
Concentration
Purification
Storage buffer
Contains
Storage conditions
Shipping conditions
RRID
Product Specific Information
Predicted to react with Mouse and Rat samples.
Target Information
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane and is involved in the conversion of progesterone to cortisol in the adrenal cortex. Mutations in this gene cause congenital adrenal hyperplasia due to 11-beta-hydroxylase deficiency. Transcript variants encoding different isoforms have been noted for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Bioinformatics
Protein Aliases: ALDOS; Aldosterone synthase; Aldosterone-synthesizing enzyme; Corticosterone 18-monooxygenase, CYP11B2; CYPXIB2; CYPXIB3; Cytochrome P-450Aldo; Cytochrome P-450C18; Cytochrome P450 11B2, mitochondrial; cytochrome P450 11B3, mitochondrial; Cytochrome P450 subfamily XIB polypeptide 2 (aldosterone synthase); cytochrome P450, family 11, subfamily B, polypeptide 2; cytochrome P450, subfamily 11B, polypeptide 2; cytochrome P450, subfamily XIB (steroid 11-beta-hydroxylase), polypeptide 2; Cytochrome P450, subfamily XIB, polypeptide 2 (aldosterone synthase); cytochrome P450-Aldo-1; cytochrome P450-Aldo-2; Cytochrome P450C11; mitochondrial cytochrome P450, family 11, subfamily B, polypeptide 2; P-450C 18; P450-Aldo-1; P450-Aldo-2; P450C 18; steroid 11-beta-hydroxylase; Steroid 11-beta-hydroxylase, CYP11B2; steroid 11-beta-monooxygenase; steroid 11-beta/18-hydroxylase; Steroid 18-hydroxylase; steroid 18-hydroxylase, aldosterone synthase, P450C18, P450aldo; steroid-11-beta-hydroxylase
Gene Aliases: ALDOS; Cp45as; CPN2; CYP11B; Cyp11b-2; CYP11B2; Cyp11b3; CYP11BL; CYPXIB2; P-450C18; P450aldo; P450C18; RNCP45AS
UniProt ID: (Human) P19099, (Mouse) P15539
Entrez Gene ID: (Human) 1585, (Mouse) 13072, (Rat) 24294
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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