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  • Primary Antibodies ›
  • CXCR1 Antibodies

Fabgennix

CXCR1 Polyclonal Antibody, FITC

View all (27) CXCR1 antibodies

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Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Cite CXCR1 Polyclonal Antibody, FITC

CXCR1 Polyclonal Antibody, FITC

Product Details

CXCR1-C-FITC

Applications
Tested Dilution
Publications

Western Blot (WB)

1:500-1:1,000
-

Immunohistochemistry (IHC)

1:50-1:250
-

ELISA (ELISA)

1:10,000
-

Immunoprecipitation (IP)

1:50-1:250
-
Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Synthetic peptide, corresponding to a region within C terminal amino acids 272-350 of Human CXCR1.
View immunogen

Conjugate

FITC FITC FITC

Excitation/Emission Max

498/517 nm View spectra spectra

Form

Liquid

Concentration

0.5-1.5 mg/mL

Purification

Affinity chromatography

Storage buffer

proprietary buffer, pH 7.4-7.8, with 0.5% BSA, 30% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C, store in dark

Shipping conditions

Ambient (domestic); Wet ice (international)

Target Information

CXCR1 is a member of the G-protein-coupled receptor family. This protein is a receptor for interleukin 8 (IL8). It binds to IL8 with high affinity, and transduces the signal through a G-protein activated second messenger system. Knockout studies in mice suggested that this protein inhibits embryonic oligodendrocyte precursor migration in developing spinal cord. This gene, IL8RB, a gene encoding another high affinity IL8 receptor, as well as IL8RBP, a pseudogene of IL8RB, form a gene cluster in a region mapped to chromosome 2q33-q36.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: C Cmotif chemokine; C X C motif chemokine; C-X-C chemokine receptor type 1; CC motif chemokine; CCmotif chemokine; CD181; CDw128a; chemokine (C-X-C motif) receptor 1; CXC; CXC motif chemokine; CXC-R1; CXCR-1; High affinity interleukin-8 receptor A; IL-8 Receptor alpha; IL-8 Receptor IL-RA; IL-8 receptor type 1; IL-8R A; IL-RA; interleukin 8 receptor, alpha; interleukin-8 receptor type 1; interleukin-8 receptor type A

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Gene Aliases: C-C; C-C-CKR-1; CD128; CD181; CDw128a; CKR-1; CMKAR1; CXCR1; IL8R1; IL8RA; IL8RBA

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UniProt ID: (Human) P25024

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Entrez Gene ID: (Human) 3577

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Function(s)
interleukin-8 receptor activity G-protein coupled receptor activity chemokine receptor activity interleukin-8 binding
Process(es)
dendritic cell chemotaxis chemotaxis inflammatory response cell surface receptor signaling pathway G-protein coupled receptor signaling pathway receptor internalization interleukin-8-mediated signaling pathway chemokine-mediated signaling pathway
It has to be done as per old AB suggested Products section.
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