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  • Primary Antibodies ›
  • CXCL10 (IP-10) Antibodies

Invitrogen

CXCL10 Recombinant Rabbit Monoclonal Antibody (2U10H3)

View all (34) CXCL10 (IP-10) antibodies

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Datasheet
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Datasheet
Protocols
Questions & Answers

Cite CXCL10 Recombinant Rabbit Monoclonal Antibody (2U10H3)

  • Antibody Testing Data (1)
CXCL10 Antibody in Western Blot (WB)
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CXCL10 Antibody in Western Blot (WB)
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CXCL10 Antibody (MA5-51325) in WB

Western blot analysis of CXCL10 in various lysates. Samples were incubated with CXCL10 Recombinant monoclonal antibody (Product # MA5-51325) using a dilution of 1:20,000 followed by HRP Goat Anti-Rabbit IgG (H+L) secondary antibody at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 180s. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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CXCL10 Antibody in Western Blot (WB)

Product Details

MA5-51325

Applications
Tested Dilution
Publications

Western Blot (WB)

1:10,000-1:20,000
-

ELISA (ELISA)

1 µg/mL
-
Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Expression System

HEK293 cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

2U10H3

Immunogen

Recombinant protein of human CXCL10/IP-10.

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1.10 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.3, with 0.05% BSA, 50% glycerol

Contains

0.05% ProClin 300

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_3093020

Target Information

IP-10 (interferon-gamma induced protein 10 kD; in mouse, also called cytokine responsive gene 2, Crg-2, or mob-1) is a highly inducible, primary response gene that belongs to the CXC chemokine superfamily. It was first cloned in 1985. The biological functions of IP-10 are still unclear. Like Mig, IP-10 has no activity on neutrophils. Its functions include stimulation of monocytes, natural killer and T-cell migration, regulation of T-cell and bone marrow progenitor maturation, modulation of adhesion molecule expression as well as inhibition of angiogenesis. Mig and IP-10 share the same receptor, CXCR3.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: 10 kDa interferon gamma-induced protein; C Cmotif chemokine; C X C motif chemokine; C-X-C motif chemokine 10; CC motif chemokine; CCmotif chemokine; chemokine (C-X-C motif) ligand 10; CXC; CXC motif chemokine; CXCL; gamma IP10; Gamma-IP10; H-IP-10; interferon-inducible cytokine IP-10; M-IP-10; protein 10 from interferon (gamma)-induced cell line; small inducible cytokine subfamily B (Cys-X-Cys), member 10; Small-inducible cytokine B10

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Gene Aliases: C7; crg-2; CXCL10; gIP-10; IFI10; INP10; IP-10; mob-1; SCYB10

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UniProt ID: (Human) P02778

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Entrez Gene ID: (Human) 3627

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Function(s)
receptor binding protein binding chemokine activity heparin binding cAMP-dependent protein kinase regulator activity CXCR3 chemokine receptor binding
Process(es)
chemotaxis inflammatory response immune response signal transduction cell surface receptor signaling pathway G-protein coupled receptor signaling pathway cell-cell signaling muscle organ development blood circulation positive regulation of cell proliferation response to cold response to gamma radiation T cell chemotaxis regulation of T cell chemotaxis response to auditory stimulus negative regulation of angiogenesis positive regulation of cAMP metabolic process response to vitamin D cellular response to heat endothelial cell activation regulation of cell proliferation positive regulation of cAMP-mediated signaling negative regulation of myoblast differentiation regulation of protein kinase activity positive regulation of transcription from RNA polymerase II promoter positive regulation of release of sequestered calcium ion into cytosol defense response to virus chemokine-mediated signaling pathway cellular response to lipopolysaccharide positive regulation of monocyte chemotaxis regulation of endothelial tube morphogenesis negative regulation of myoblast fusion positive regulation of T cell migration
It has to be done as per old AB suggested Products section.
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