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  • Primary Antibodies ›
  • CXCL1 (GRO alpha) Antibodies

Invitrogen

CXCL1 Polyclonal Antibody

2 References
View all (31) CXCL1 (GRO alpha) antibodies

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Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Cite CXCL1 Polyclonal Antibody

  • Antibody Testing Data (4)
CXCL1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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CXCL1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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FIGURE: 1 / 4

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CXCL1 Antibody (PA5-115328) in IHC (P)

Immunohistochemistry analysis of CXCL1 in mouse testis tissue. Samples were treated with formaldehyde and treated with citrate buffer for antigen retrieval, blocked, and incubated (1.5 hours at 22°C) with polyclonal antibody (Product # PA5-115328) at a dilution of 1:100. Secondary staining was applied with HRP conjugated anti-Rabbit. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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CXCL1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
CXCL1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
CXCL1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
CXCL1 Antibody in Western Blot (WB)
CXCL1 Polyclonal Antibody

Product Details

PA5-115328

Applications
Tested Dilution
Publications

Western Blot (WB)

1:500-1:2,000
View 1 publication 1 publication

Immunohistochemistry (IHC)

-
View 1 publication 1 publication

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200
-

Immunocytochemistry (ICC/IF)

1:100-1:500
-
Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

A synthesized peptide derived from human CXCL1(Accession P09341), corresponding to amino acid residues N56-S106.
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2899964

Product Specific Information

Antibody detects endogenous levels of total GRO alpha.

Target Information

CXCL1, CXCL2, and CXCL3, also known respectively as GRO alpha, GRO beta (MIP-2 alpha) and GRO gamma (MIP-2 beta), are members of the CXC subfamily of chemokines. Mature CXCL1/2/3 proteins bind with high affinity to the IL-8 receptor type B and are potent neutrophil attractants and activators. In vitro, the processed forms GRO-alpha(4-73), GRO-alpha(5-73) and GRO-alpha(6-73) show a 30-fold higher chemotactic activity.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Bioinformatics

Protein Aliases: alpha-chemokine; C Cmotif chemokine; C X C motif chemokine; C-X-C motif chemokine 1; CC motif chemokine; CCmotif chemokine; chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha); CINC-1; CXC; CXC motif chemokine; CXCL; CXCL-1; Cytokine-induced neutrophil chemoattractant 1; fibroblast secretory protein; gro; GRO a; GRO α; GRO-alpha(1-73); GRO1 oncogene; GRO1 oncogene (melanoma growth stimulating activity, alpha); GRO1 oncogene (melanoma growth-stimulating activity); GROalpha; Growth-regulated alpha protein; GROα; KC/GR)-alpha; KC/GRO-alpha; melanoma growth stimulating activity, alpha; Melanoma growth stimulatory activity; melanoma growth stimulatory activity alpha; MGSA; MGSA alpha; NAP-3; NAP3; Neutrophil-activating protein 3; Platelet-derived growth factor-inducible protein KC; Secretory protein N51

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Gene Aliases: CINC-1; Cinc1; CXCL1; FSP; GRO; GRO1; GROA; KC; MGSA; MGSA-a; N51; NAP-3; SCYB1

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UniProt ID: (Human) P09341, (Rat) P14095, (Mouse) P12850

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Entrez Gene ID: (Human) 2919, (Rat) 81503, (Mouse) 14825

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Function(s)
receptor binding chemokine activity enzyme activator activity growth factor activity CXCR chemokine receptor binding cytokine activity
Process(es)
chemotaxis inflammatory response immune response signal transduction G-protein coupled receptor signaling pathway nervous system development cell proliferation negative regulation of cell proliferation actin cytoskeleton organization response to lipopolysaccharide intracellular signal transduction positive regulation of catalytic activity cell chemotaxis chemokine-mediated signaling pathway positive regulation of neutrophil chemotaxis response to amphetamine response to molecule of bacterial origin acute inflammatory response positive regulation of leukocyte chemotaxis positive regulation of cytosolic calcium ion concentration response to heat response to gamma radiation positive regulation of sodium ion transport neutrophil chemotaxis response to estradiol positive regulation of superoxide anion generation regulation of cell proliferation positive regulation of potassium ion transport response to glucocorticoid positive regulation of neutrophil mediated killing of fungus positive regulation of hematopoietic stem cell proliferation
It has to be done as per old AB suggested Products section.
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Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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