Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Invitrogen
CUG-BP2 Monoclonal Antibody (D7-B5)
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
FIGURE: 1 / 3
CUG-BP2 Antibody (MA5-42409) in IHC (P)
Product Details
MA5-42409
Species Reactivity
Host/Isotype
Class
Type
Clone
Immunogen
Conjugate
Form
Concentration
Purification
Storage buffer
Contains
Storage conditions
Shipping conditions
RRID
Product Specific Information
Positive Control: MCF-7 cell lysate, A549 cell lysate, PC-3M cell lysate, rat brain tissue, mouse brain tissue.
Subcellular Location: Cytoplasm, Nucleus.
Target Information
CUG-BP1 and CUG-BP2 are proteins that bind specifically to (CUG)8 oligonucleotides in vitro. While CUG-BP1 has the major binding activity in normal cells, nuclear CUG-BP2 binding activity increases in DM cells. Both CUG-BP1 and CUG-BP2 are isoforms of a novel heterogeneous nuclear ribonucleoprotein (hnRNP), hNab50. CUG-BP1, an RNA CUG triplet repeat binding protein, regulates splicing and translation of various RNAs. Expansion of RNA CUG repeats in the DMPK in DM is associated with alterations in binding activity of CUG-BP1 as well as alterations in the translation of the C/EBPb transcription factor. CUG-BP1 is an important regulator of initiation from different AUG codons of C/EBPb mRNA.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Bioinformatics
Protein Aliases: Bruno-like protein 3; CELF 2; CELF-2; CUG triplet repeat RNA-binding protein 2; CUG triplet repeat, RNA binding protein 2; CUG-BP- and ETR-3-like factor 2; CUG-BP2; CUGBP Elav-like family member 2; Cugbp- and Etr3-like factor 2; ELAV-type RNA-binding protein 3; ETR-3; hNAPOR; mNapor; neur; Neuroblastoma apoptosis-related RNA-binding protein; RNA-binding protein BRUNOL-3; RNA-binding protein Brunol3; rNapor; RP23-124P7.1
Gene Aliases: B230218O03; B230345P09Rik; BRUNOL3; C88023; CELF-2; CELF2; CUG-BP2; CUGBP2; D230046B21Rik; ETR-3; ETR3; mETR-3; NAPOR; Napor-2
UniProt ID: (Human) O95319, (Rat) Q792H5, (Mouse) Q9Z0H4
Entrez Gene ID: (Human) 10659, (Rat) 29428, (Mouse) 14007
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support