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  • Primary Antibodies ›
  • CUBN Antibodies

Invitrogen

CUBN Polyclonal Antibody

View all (8) CUBN antibodies

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Datasheet
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Datasheet
Protocols
Questions & Answers

Cite CUBN Polyclonal Antibody

  • Antibody Testing Data (1)
CUBN Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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CUBN Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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CUBN Antibody (PA5-80524) in IHC (P)

Immunohistochemical analysis of CUBN in formalin-fixed paraffin embedded human kidney tissue sections using a CUBN Polyclonal Antibody (Product # PA5-80524) at a 1:1000 dilution. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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CUBN Antibody in Immunohistochemistry (Paraffin) (IHC (P))

Product Details

PA5-80524

Applications
Tested Dilution
Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:500-1:2,000
-
Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

A synthetic peptide corresponding to the center region of the Human cubilin/CUBN

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A, Antigen affinity chromatography

Storage buffer

PBS

Contains

no preservative

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2787828

Product Specific Information

This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%).

This antibody has specificity for Human cubilin/CUBN.

Target Information

Cubilin (CUBN) acts as a receptor for intrinsic factor-vitamin B12 complexes. The role of receptor is supported by the presence of 27 CUB domains. Cubulin is located within the epithelium of intestine and kidney. Mutations in CUBN may play a role in autosomal recessive megaloblastic anemia.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: 460 kDa receptor; Cubilin; cubilin (intrinsic factor-cobalamin receptor); cubilin precursor variant 1; cubilin precursor variant 2; cubilin precursor variant 3; Cubulin; Intestinal intrinsic factor receptor; Intrinsic factor-cobalamin receptor; Intrinsic factor-vitamin B12 receptor

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Gene Aliases: CUBN; gp280; IFCR; MGA1

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UniProt ID: (Human) O60494

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Entrez Gene ID: (Human) 8029

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Function(s)
receptor activity transporter activity calcium ion binding protein binding cobalamin binding protein homodimerization activity
Process(es)
tissue homeostasis receptor-mediated endocytosis cholesterol metabolic process cobalamin metabolic process protein transport cobalamin transport lipoprotein metabolic process vitamin D metabolic process lipoprotein transport
It has to be done as per old AB suggested Products section.
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Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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