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  • CTR1 Antibodies

Invitrogen

CTR1 Polyclonal Antibody

View all (19) CTR1 antibodies

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Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Cite CTR1 Polyclonal Antibody

  • Antibody Testing Data (2)
CTR1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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CTR1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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FIGURE: 1 / 2

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CTR1 Antibody (PA5-115912) in IHC (P)

Immunohistochemistry analysis of CTR1 in rat lung tissue. Samples were treated with formaldehyde and treated with citrate buffer for antigen retrieval, blocked, and incubated (1.5 hours at 22°C) with polyclonal antibody (Product # PA5-115912) at a dilution of 1:100. Secondary staining was applied with HRP conjugated anti-Rabbit. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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CTR1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
CTR1 Antibody in Western Blot (WB)
CTR1 Polyclonal Antibody

Product Details

PA5-115912

Applications
Tested Dilution
Publications

Western Blot (WB)

1:500-1:2,000
-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200
-
Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

A synthesized peptide derived from human SLC31A1(Accession O15431), corresponding to amino acid residues H3-N53.
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2900546

Product Specific Information

Antibody detects endogenous levels of total SLC31A1 / CTR1.

Target Information

The trace metal copper (Cu) plays a crucial role in mammalian cells as a cofactor for many enzymes. Cu-related genetic diseases, such as Menkes disease and Wilson disease, arise from a lack of Cu homeostasis in mammalian cells. CTR1 is a high-affinity copper-uptake protein. The C-terminal domain is similar to the Raf family of protein kinases, but it's first two-thirds encodes a novel protein domain. CTR1 provides the primary avenue for copper uptake in mammalian cells, thereby, affecting Cu homeostasis and embryonic development.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: copper transport 1 homolog; Copper transporter 1; Copper uptake transporter 1; CTR1; hCTR1; High affinity copper uptake protein 1; Liver regeneration-related protein LRRGT00200; rCTR1; solute carrier family 13 (sodium/sulphate symporters), member 1; solute carrier family 31 (copper transporter), member 1; solute carrier family 31 (copper transporters), member 1; Solute carrier family 31 member 1

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Gene Aliases: 4930445G01Rik; AI787263; AU016967; COPT1; CTR1; LRRGT00200; SLC31A1

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UniProt ID: (Human) O15431, (Rat) Q9JK41, (Mouse) Q8K211

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Entrez Gene ID: (Human) 1317, (Rat) 171135, (Mouse) 20529

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Function(s)
copper ion transmembrane transporter activity copper uptake transmembrane transporter activity protein binding
Process(es)
copper ion transport drug transmembrane transport cellular copper ion homeostasis copper ion transmembrane transport cellular response to cisplatin copper ion import into cell copper ion import transport ion transport
It has to be done as per old AB suggested Products section.
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Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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