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Invitrogen
CTHRC1 Polyclonal Antibody
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Product Details
PA5-38054
Species Reactivity
Host/Isotype
Class
Type
Immunogen
Conjugate
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RRID
Product Specific Information
A recommended positive control is rat small intestine tissue lysate.
At least two isoforms of CTHRC1 are known to exist; this antibody will detect only the larger isoform.
Target Information
The Collagen triple helix repeat-containing protein (CTHRC1) is a glycosylated, secreted protein that is transiently expressed in the arterial wall in response to injury where it is thought to contribute to vascular remodeling by inhibiting collagen expression and deposition and promoting cell migration. CTHRC1 is highly expressed multiple human cancers, including pancreatic cancer where it plays a significant role in the progression and metastasis of the disease by regulating migration and adhesion of tumors cells. CTHRC1 overexpression can also be used as an independent prognostic marker in gastric cancer. Mutations at this locus have been associated with Barrett esophagus and esophageal adenocarcinoma.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Bioinformatics
Protein Aliases: Collagen triple helix repeat-containing protein 1
Gene Aliases: 1110014B07Rik; CTHRC1; UNQ762/PRO1550
UniProt ID: (Human) Q96CG8, (Mouse) Q9D1D6, (Rat) Q8CG08
Entrez Gene ID: (Human) 115908, (Mouse) 68588, (Rat) 282836
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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