Abnova

CTH Monoclonal Antibody (S51)

Name: CTH Monoclonal Antibody (S51)
Brand: Abnova
SKU: H00001491-M03

View all (27) CTH antibodies

Datasheet

Protocols

Questions & Answers

Datasheet

Protocols

Questions & Answers

Antibody Testing Data (5)

CTH Antibody in Immunohistochemistry (Paraffin) (IHC (P))

FIGURE: 1 / 5

CTH Antibody (H00001491-M03) in IHC (P)

Immunoperoxidase of monoclonal antibody to CTH on formalin-fixed paraffin-embedded human pancreas. Antibody concentration is 3 µg/mL.

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Immunogen image

Immunogen Image CTH Monoclonal Antibody (S51)

Product Details

H00001491-M03

Applications

Tested Dilution

Publications

Western Blot (WB)

1-5 µg/mL

Immunohistochemistry (Paraffin) (IHC (P))

3 µg/mL

ELISA (ELISA)

1 ng/mL

Product Specifications

Species Reactivity

Human, Mouse

Host/Isotype

Mouse / IgG1, kappa

Class

Monoclonal

Type

Antibody

Clone

S51

Immunogen

CTH (AAH15807, 1 a.a. approximately 405 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

See Label

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4

Contains

no preservative

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Sequence of this protein is as follows: MQEKDASSQG FLPHFQHFAT QAIHVGQDPE QWTSRAVVPP ISLSTTFKQG APGQHSGFEY SRSGNPTRNC LEKAVAALDG AKYCLAFASG LAATVTITHL LKAGDQIICM DDVYGGTNRY FRQVASEFGL KISFVDCSKI KLLEAAITPE TKLVWIETPT NPTQKVIDIE GCAHIVHKHG DIILVVDNTF MSPYFQRPLA LGADISMYSA TKYMNGRSDV VMGLVSVNCE SLHNRLRFLQ NSLGAVPSPI DCYLCNRGLK TLHVRMEKHF KNGMAVAQFL ESNPWVEKVI YPGLPSHPQH ELVKRQCTGC TGMVTFYIKG TLQHAEIFLK NLKLFTLAES LGGFESLAEL PAIMTHASVL KNDRDVLGIS DTLIRLSVGL EDEEDLLEDL DQALKAAHPP SGSHS

Target Information

This gene encodes a cytoplasmic enzyme in the trans-sulfuration pathway that converts cystathione derived from methionine into cysteine. Glutathione synthesis in the liver is dependent upon the availability of cysteine. Mutations in this gene cause cystathioninuria. Alternative splicing of this gene results in two transcript variants encoding different isoforms.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: CGL; cystathionase (cystathionine gamma-lyase); Cystathionine gamma-lyase; Cysteine desulfhydrase; Cysteine-protein sulfhydrase; Gamma-cystathionase; Homocysteine desulfhydrase; homoserine deaminase; homoserine dehydratase; MGC9471

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Gene Aliases: 0610010I13Rik; AI314617; BC019483; CSE; CTH; Cys3

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UniProt ID: (Human) P32929, (Mouse) Q8VCN5

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Entrez Gene ID: (Human) 1491, (Mouse) 107869

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Function(s)

cystathionine gamma-synthase activity cystathionine gamma-lyase activity protein binding calmodulin binding carbon-sulfur lyase activity pyridoxal phosphate binding L-cystine L-cysteine-lyase (deaminating) homocysteine desulfhydrase activity L-cysteine desulfhydrase activity catalytic activity cystathionine beta-lyase activity lyase activity

Process(es)

sulfur amino acid catabolic process cysteine metabolic process protein-pyridoxal-5-phosphate linkage via peptidyl-N6-pyridoxal phosphate-L-lysine cysteine biosynthetic process via cystathionine cysteine biosynthetic process transsulfuration endoplasmic reticulum unfolded protein response positive regulation of I-kappaB kinase/NF-kappaB signaling protein sulfhydration positive regulation of NF-kappaB transcription factor activity protein homotetramerization hydrogen sulfide biosynthetic process 'de novo' L-methionine biosynthetic process positive regulation of aortic smooth muscle cell differentiation negative regulation of apoptotic signaling pathway glutathione metabolic process negative regulation of cell proliferation cellular amino acid biosynthetic process negative regulation of cell growth negative regulation of apoptotic process homocysteine metabolic process

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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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CTH Monoclonal Antibody (S51)

CTH Antibody (H00001491-M03) in IHC (P)

Product Details

H00001491-M03

Western Blot (WB)

Immunohistochemistry (Paraffin) (IHC (P))

ELISA (ELISA)

Species Reactivity

Host/Isotype

Class

Type

Clone

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

References (0)

Bioinformatics

Performance Guarantee

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