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Bioss
CTDSPL Polyclonal Antibody
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FIGURE: 1 / 1
CTDSPL Antibody (BS-8241R) in Flow
Product Details
BS-8241R
Species Reactivity
Host/Isotype
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Type
Immunogen
Conjugate
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Target Information
Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells. Preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residue repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation. [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Bioinformatics
Protein Aliases: Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 3; CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like; CTD small phosphatase-like protein; CTDSP-like; hYA22; MGC71888; NIF-like protein; NLI-interacting factor 1; Nuclear LIM interactor-interacting factor 1; Protein YA22; RB protein serine phosphatase from chromosome 3; RBSP3; SCP-3; SCP3; SCP3 COR1; Small C-terminal domain phosphatase 3; small CTD phosphatase 3
Gene Aliases: 2810418J22Rik; AI426263; C3orf8; CTDSPL; HYA22; NIF1; NIFL; PSR1; RBSP3; SCP3; YA22
UniProt ID: (Human) O15194, (Mouse) P58465
Entrez Gene ID: (Human) 10217, (Mouse) 69274, (Rat) 301056
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