Invitrogen

CRHR2 Polyclonal Antibody

View all (15) CRHR2 antibodies

{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}

{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}

{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}

Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers
CRHR2 Polyclonal Antibody

Product Details

PA5-33451

Applications
Tested Dilution
Publications

Immunohistochemistry (Paraffin) (IHC (P))

34 µg/mL
-
Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Synthetic 17 amino acid peptide from N-terminal extracellular domain of human CRHR2.
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS

Contains

0.1% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2550831

Product Specific Information

Percent identity with other species by BLAST analysis: Human (100%) Gorilla (88%).

Target Information

Corticotropin-releasing hormone (CRH; 122560) is a 41-amino acid peptide synthesized in the hypothalamus, and play a role in the neuroregulation, responses to stress and immune challenge. Corticotropin Releasing Factor Receptor 2 (CRHR2) was the receptor of CRH. The sepression of CRHR2 has been reported in various regions of the brain as well as in placenta, umbilical vein, heart, epididymis, gastrointestinal tract, adrenal and skeletal muscle.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

References (0)

Have you cited this product in a publication?
Let us know so we can reference it here.
Cite this product

Bioinformatics

Protein Aliases: Corticotropin-releasing factor receptor 2; Corticotropin-releasing hormone receptor 2; CRF-R-2; CRF2 receptor, beta isoform; CRH receptor 2 variant B; CRH-R-2; CRH-R2; Crh2 receptor

View more View less

Gene Aliases: CRF-RB; CRF2; CRF2R; CRFR2; CRH2R; CRHR2; HM-CRF

View more View less

UniProt ID: (Human) Q13324

View more View less

Entrez Gene ID: (Human) 1395

View more View less

Function(s)
protein binding corticotrophin-releasing factor receptor activity peptide hormone binding corticotropin-releasing hormone receptor activity
Process(es)
actin filament organization cell surface receptor signaling pathway adenylate cyclase-modulating G-protein coupled receptor signaling pathway protein kinase C-activating G-protein coupled receptor signaling pathway hormone-mediated signaling pathway positive regulation of heart rate positive regulation of gene expression negative regulation of gene expression negative regulation of norepinephrine secretion positive regulation of serotonin secretion sensory perception of pain cerebellum development hypothalamus development negative regulation of cAMP biosynthetic process positive regulation of cAMP biosynthetic process epithelial cell differentiation positive regulation of interleukin-6 production negative regulation of epinephrine secretion positive regulation of stress-activated MAPK cascade negative regulation of luteinizing hormone secretion gastric motility catecholamine biosynthetic process positive regulation of blood pressure negative regulation of follicle-stimulating hormone secretion skeletal muscle tissue growth positive regulation of NF-kappaB transcription factor activity long-term synaptic potentiation negative regulation of insulin secretion involved in cellular response to glucose stimulus regulation of ERK1 and ERK2 cascade cellular response to corticotropin-releasing hormone stimulus cellular response to glucocorticoid stimulus negative regulation of calcium ion import negative regulation of feeding behavior negative regulation of defecation
guarantee_icon

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

Learn more
help_icon

We're here to help

Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.

Contact tech support