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  • CREB3L1 Antibodies

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CREB3L1/OASIS Monoclonal Antibody (2B5B4), CoraLite® Plus 488

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Questions & Answers

Cite CREB3L1/OASIS Monoclonal Antibody (2B5B4), CoraLite® Plus 488

  • Antibody Testing Data (1)
CREB3L1/OASIS Antibody in Flow Cytometry (Flow)
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CREB3L1/OASIS Antibody in Flow Cytometry (Flow)
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CREB3L1/OASIS Antibody (CL488-67617) in Flow

1X10^6 HepG2 cells were intracellularly stained with 0.4 µg CoraLite® Plus 488 Anti-Human CREB3L1,OASIS (CL488-67617, Clone:2B5B4) (red), or 0.4 µg x. Cells were fixed with 4% PFA and permeabilized with Flow Cytometry Perm Buffer (PF00011-C). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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CREB3L1/OASIS Antibody in Flow Cytometry (Flow)
CREB3L1/OASIS Monoclonal Antibody (2B5B4), CoraLite® Plus 488

Product Details

CL488-67617

Applications
Tested Dilution
Publications

Flow Cytometry (Flow)

0.4 µg/1x10^6 cell suspension
-
Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

2B5B4

Immunogen

Recombinant protein
View immunogen

Conjugate

CoraLite® Plus 488 CoraLite® Plus 488 CoraLite® Plus 488
  • Unconjugated
  • Request custom conjugation

Excitation/Emission Max

493/522 nm

Form

Liquid

Purification

Protein G

Storage buffer

PBS with 50% glycerol, 0.5% BSA

Contains

0.05% ProClin 300

Storage conditions

-20°C, store in dark

Shipping conditions

Wet ice

Product Specific Information

Immunogen sequence: PHQAPGEMTQ LPVIKAEPLE VNQFLKVTPE DLVQMPPTPP SSHGSDSDGS QSPRSLPPSS PVRPMARSST AISTSPLLTA PHKLQGTSGP LLLTEEEKRT LIAEGYPIPT KLPLTKAEEK ALKRVRRKIK NKISAQESRR KKKEYVECLE KKVETFTSEN NELWKKVETL ENANRTLLQQ LQKLQTLVTN KISRPYKMAA TQTGTCLMVA ALCFVLVLGS LVPCLPEFSS GSQTVKEDPL AADGVYTASQ MPSRSLLFYD DGAGLWEDGR STLLPMEPPD GWEINPGGPA EQRPRDHLQH DHLDSTHETT KYLSEAWPKD GGNGTSPDFS HSKEWFHDRD LGPNTTIKLS

Target Information

Transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. Specifically involved in ER-stress response in astrocytes in the central nervous system. May play a role in gliosis. In vitro, binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: BBF-2 homolog; cAMP responsive element binding protein 3-like 1; cAMP-responsive element-binding protein 3-like protein 1; Cyclic AMP-responsive element-binding protein 3-like protein 1; OASIS; old astrocyte specifically induced substance; Old astrocyte specifically-induced substance

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Gene Aliases: CREB3L1; OASIS; PSEC0238

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UniProt ID: (Human) Q96BA8, (Mouse) Q9Z125, (Rat) Q66HA2

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Entrez Gene ID: (Human) 90993, (Mouse) 26427, (Rat) 362165

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Function(s)
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding chromatin binding protein binding cAMP response element binding sequence-specific DNA binding transcription regulatory region DNA binding DNA binding transcription factor activity, sequence-specific DNA binding
Process(es)
osteoblast differentiation transcription from RNA polymerase II promoter multicellular organism development endoplasmic reticulum unfolded protein response extracellular matrix constituent secretion negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress transcription, DNA-templated regulation of transcription, DNA-templated response to unfolded protein regulation of ossification positive regulation of transcription from RNA polymerase II promoter regulation of bone mineralization
It has to be done as per old AB suggested Products section.
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