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Proteintech
COX11 Polyclonal Antibody
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Product Details
11498-1-AP
Species Reactivity
Host/Isotype
Class
Type
Immunogen
Conjugate
Form
Concentration
Purification
Storage buffer
Contains
Storage conditions
Shipping conditions
Product Specific Information
Immunogen sequence: MGGLWRPGW RCVPFCGWRW IHPGSPTRAA ERVEPFLRPE WSGTGGAERG LRWLGTWKRC SLRARHPALQ PPRRPKSSNP FTRAQEEERR RQNKTTLTYV AAVAVGMLGA SYAAVPLYRL YCQTTGLGGS AVAGHASDKI ENMVPVKDRI IKISFNADVH ASLQWNFRPQ QTEIYVVPGE TALAFYRVKN PTDKPVIGIS TYNIVPFEAG QYFNKIQCFC FEEQRLNPQE EVDMPVFFYI DPEFAEDPRM IKVDLITLSY TFFEAKEGHK LPVPGYN (1-276 aa encoded by BC005895)
Target Information
Cytochrome c oxidase (COX) is the terminal enzyme in the electron transfer chain, functioning as a transmembrane proton pump that builds an electrochemical gradient with chemical energy from the reduction of O2. Cytochrome c oxidase assembly protein COX11 is an intracellular mitochondrial membrane protein necessary for the construction of an active COX complex. COX11 contains a single transmembrane helix downstream of the N-terminal, mitochondrial targeting sequence and a C-terminal Cu(I)-binding domain. The assembly of COX requires the delivery of metal cofactors. Along with COX12 and SCO1/2, COX11 acts as a metal ion chaperone necessary for copper insertion into CuA and CuB redox-active copper centers of COX in eukaryotes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: COX11 cytochrome c oxidase copper chaperone; COX11 homolog, cytochrome c oxidase assembly protein; cytochrome c oxidase assembly homolog 11; cytochrome c oxidase assembly protein 11; Cytochrome c oxidase assembly protein COX11, mitochondrial; cytochrome c oxidase subunit 11
Gene Aliases: 2010004I09Rik; COX11; COX11P
UniProt ID: (Human) Q9Y6N1, (Mouse) Q6P8I6
Entrez Gene ID: (Human) 1353, (Mouse) 69802, (Rat) 690300
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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