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Invitrogen
COMMD5 Polyclonal Antibody
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Product Details
PA5-95782
Species Reactivity
Host/Isotype
Class
Type
Immunogen
Conjugate
Form
Concentration
Purification
Storage buffer
Contains
Storage conditions
Shipping conditions
RRID
Product Specific Information
Immunogen sequence: MSAVGAATPY LHHPGDSHSG RVSFLGAQLP PEVAAMARLL GDLDRSTFRK LLKFVVSSLQ GEDCREAVQR LGVSANLPEE QLGALLAGMH TLLQQALRLP PTSLKPDTFR DQLQELCIPQ DLVGDLASVV FGSQRPLLDS VAQQQGAWLP HVADFRWRVD VAISTSALAR SLQPSVLMQL KLSDGSAYRF EVPTAKFQEL RYSVALVLKE MADLEKRCER RLQD; Positive Samples: SGC996, 293T, LO2, HeLa, A-431, Mouse kidney, Rat liver; Cellular Location: Cytoplasm, Nucleus
Target Information
COMMD5 is a protein coding gene. May modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes. Negatively regulates cell proliferation. Negatively regulates cell cycle G2/M phase transition probably by transactivating p21/CDKN1A through the p53/TP53-independent signaling pathway. Involved in kidney proximal tubule morphogenesis. Down-regulates activation of NF-kappa-B.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Bioinformatics
Protein Aliases: COMM domain-containing protein 5; FLJ13008; HCaRG; hypertension-related calcium regulated; Hypertension-related calcium-regulated gene protein; hypertension-related, calcium regulated
Gene Aliases: 2310065H03Rik; AI854466; COMMD5; D15Ertd81e; HCARG; HT002
UniProt ID: (Human) Q9GZQ3, (Rat) Q9ERR2, (Mouse) Q8R395
Entrez Gene ID: (Human) 28991, (Rat) 245974, (Mouse) 66398
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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